Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Accrued Liabilities [Abstract]
Accrued external research, development and manufacturing costs	$ 44,919	$ 48,590
Accrued professional and consultant fees	4,142	2,155
Accrued employee compensation	3,443	4,945
Other	120	587
Accrued Expenses	$ 52,624	$ 56,277