X0306 4 2022-06-22 0 0001832038 Adagio Therapeutics, Inc. ADGI 0001201256 WYZGA MICHAEL S C/O ADAGIO THERAPEUTICS, INC. 1601 TRAPELO ROAD, SUITE 178 WALTHAM MA 02451 1 0 0 0 Stock Option (Right to Buy) 3.09 2022-06-22 4 A 0 75000 0.00 A 2032-06-21 Common Stock 75000 75000 D This option was granted on June 22, 2022 and vests in full on the earlier of (i) June 22, 2023 or (ii) the date of the Issuer's 2023 Annual Meeting of Stockholders, subject to continued service through the vesting date. /s/ Jane Henderson attorney-in-fact for Michael Wyzga 2022-06-24