ACLARIS THERAPEUTICS INC COM 00461U105 39905 2314648 SH SOLE 2314648 0 0 BCLS ACQUISITION CORP COM CL A G0904B105 2468 250000 SH SOLE 250000 0 0 BELLUS HEALTH INC NEW COM NEW 07987C204 38787 5637630 SH SOLE 5637630 0 0 C4 THERAPEUTICS INC COM STK 12529R107 11671 481094 SH SOLE 481094 0 0 COGENT BIOSCIENCES INC COM 19240Q201 26221 3500768 SH SOLE 3500768 0 0 CELCUITY INC COM 15102K100 8606 920464 SH SOLE 920464 0 0 CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202 8215 241199 SH SOLE 241199 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 17847 5738500 SH SOLE 5738500 0 0 CYTOKINETICS INC COM NEW 23282W605 31460 854652 SH SOLE 854652 0 0 DYNE THERAPEUTICS INC COM 26818M108 2941 305125 SH SOLE 305125 0 0 GENOCEA BIOSCIENCES INC COM NEW 372427401 3850 3079756 SH SOLE 3079756 0 0 IVERIC BIO INC COM 46583P102 37278 2214961 SH SOLE 2214961 0 0 IMMUNIC INC COM 4525EP101 10091 893013 SH SOLE 893013 0 0 INVENTIVA SA ADS 46124U107 2994 262658 SH SOLE 262658 0 0 KALVISTA PHARMACEUTICALS INC COM 483497103 4607 312553 SH SOLE 312553 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 26245 3561052 SH SOLE 3561052 0 0 KURA ONCOLOGY INC COM 50127T109 12486 776514 SH SOLE 776514 0 0 MEREO BIOPHARMA GROUP PLC ADS 589492107 2190 1954970 SH SOLE 1954970 0 0 MERUS N V COM N5749R100 48026 1816421 SH SOLE 1816421 0 0 PMV PHARMACEUTICALS INC COM 69353Y103 2603 125000 SH SOLE 125000 0 0 PROTAGONIST THERAPEUTICS INC COM 74366E102 7859 331886 SH SOLE 331886 0 0 SATSUMA PHARMACEUTICALS INC COM 80405P107 14103 3711286 SH SOLE 3711286 0 0 TENAYA THERAPEUTICS INC COM 87990A106 6054 513930 SH SOLE 513930 0 0 TRICIDA INC COM 89610F101 14340 1744570 SH SOLE 1744570 0 0 VIRIDIAN THERAPEUTICS INC COM 92790C104 17590 951339 SH SOLE 951339 0 0 VISTAGEN THERAPEUTICS INC COM NEW 92840H202 12521 10097229 SH SOLE 10097229 0 0 XENON PHARMACEUTICALS INC COM 98420N105 36764 1202613 SH SOLE 1202613 0 0