X0407 4 2023-04-06 0001831868 SeaStar Medical Holding Corp ICU 0001613111 Van Heel Kenneth C/O SEASTAR MEDICAL HOLDING CORPORATION 3513 BRIGHTON BLVD., SUITE 410 DENVER CO 80216 true false Common Stock, par value $0.0001 per share 2023-04-06 4 A 0 7978 0 A 16400 D Stock Option (Right to Buy) 1.84 2023-04-06 4 A 0 11967 0 A 2033-04-06 Common Stock 11967 11967 D Stock Option (Right to Buy) 0.55 2031-10-14 Common Stock 24483 24483 D Represents the Issuer's common stock subject to restricted stock units (RSUs), all of which will vest on the first anniversary of the date of grant. All options reported herein will vest, subject to continued service, on the first anniversary of the date of grant. The option vests with respect to (i) twenty-five percent (25%) of the shares upon completion of one (1) year of service measured from October 14, 2021 and (ii) the balance of the shares subject to the option in a series of thirty-six (36) successive equal monthly installments upon completion of each additional month of service over the thirty-six (36)-month period measured from October 14, 2022. /s/ Eric Schlorff, as attorney-in-fact 2023-04-10