<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001853317</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Class A Common Stock</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>03/31/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001831840</issuerCik>
        <issuerName>SEMRUSH HOLDINGS, INC.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>81686C104</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <street1 xmlns="http://www.sec.gov/edgar/common">800 BOYLSTON STREET</street1>
          <street2 xmlns="http://www.sec.gov/edgar/common">SUITE 2475</street2>
          <city xmlns="http://www.sec.gov/edgar/common">BOSTON</city>
          <stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
          <zipCode xmlns="http://www.sec.gov/edgar/common">02199</zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>SEMR Holdings Limited</reportingPersonName>
      <citizenshipOrOrganization>G4</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>0</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>0</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>0</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>SEMRUSH HOLDINGS, INC.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>800 BOYLSTON STREET, SUITE 2475, BOSTON, MA 02199</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>SEMR Holdings Limited</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>2-4 Arch. Makarios III Avenue, 9th Floor, Capital Centre, Nicosia, P.C., Cyprus 1065</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Cyprus</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</amountBeneficiallyOwned>
        <classPercent>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>The information requested by this paragraph is incorporated herein by reference to the cover page to this Schedule 13G/A.</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>N</notApplicableFlag>
        <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>SEMR Holdings Limited</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Joshua Posner</signature>
        <title>Joshua Posner/Authorized Signatory</title>
        <date>04/14/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
