75000 - Document - Document and Entity Information
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75010 - Statement - Balance Sheets
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75020 - Statement - Balance Sheets (Parenthetical)
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75030 - Statement - Statements of Operations and Comprehensive Loss
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75040 - Statement - Statements of Stockholders' Equity
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75050 - Statement - Statements of Cash Flows
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995457 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995467 - Disclosure - Organization and Description of the Business
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995477 - Disclosure - Summary of Significant Accounting Policies
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995487 - Disclosure - Other Financial Statement Information
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995497 - Disclosure - Cash, Cash Equivalents, and Marketable Securities
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995517 - Disclosure - Non-Marketable Equity Securities
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995527 - Disclosure - Leases
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995537 - Disclosure - Note Payable
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995547 - Disclosure - Stockholders' Equity
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995557 - Disclosure - Stock Compensation
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995567 - Disclosure - Employee Benefit Plans
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995577 - Disclosure - Licenses and Collaborations
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995587 - Disclosure - Income Taxes
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995597 - Disclosure - Commitments and Contingencies
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995607 - Disclosure - Restructuring and Related Activities
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995617 - Disclosure - Net Loss Per Share Attributable to Common Stockholders
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995627 - Disclosure - Related Party Transactions
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995637 - Disclosure - Segment Reporting
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995647 - Disclosure - Subsequent Events
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995657 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995667 - Disclosure - Other Financial Statement Information (Tables)
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995677 - Disclosure - Cash, Cash Equivalents, and Marketable Securities (Tables)
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995687 - Disclosure - Non-Marketable Equity Securities (Tables)
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995697 - Disclosure - Leases (Tables)
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995707 - Disclosure - Note Payable (Table)
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995717 - Disclosure - Stock Compensation (Table)
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995727 - Disclosure - Income Taxes (Tables)
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995737 - Disclosure - Net Loss Per Share Attributable to Common Stockholders (Tables)
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995747 - Disclosure - Segment Reporting (Tables)
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995757 - Disclosure - Organization and Description of the Business - Additional Information (Details)
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995767 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995777 - Disclosure - Other Financial Statement Information - Schedule Of Prepaid Expenses and Other Current Assets (Details)
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995787 - Disclosure - Other Financial Statement Information - Schedule Of Prepaid Expenses and Other Current Assets (Details) 2
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995797 - Disclosure - Other Financial Statement Information - Schedule Of Accrued Expenses And Other Current Liabilities (Details)
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995807 - Disclosure - Cash, Cash Equivalents, and Marketable Securities - Additional Information (Details)
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995817 - Disclosure - Cash, Cash Equivalents, and Marketable Securities - Summarizes the Unrealized Gains and Losses in Fair Value of the Company's Investments in Debt Securities (Details)
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995827 - Disclosure - Cash, Cash Equivalents And Marketable Securities - Schedule of Estimated Fair Value of Marketable Securities by Stated Contractual Maturities (Details)
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995837 - Disclosure - Non-Marketable Equity Securities - Summary of Non-marketable Equity Securities (Details)
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995847 - Disclosure - Leases - Schedule of Lease Cost (Details)
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995857 - Disclosure - Leases - Schedule of Other Supplemental Information Related to Operating Leases (Details)
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995867 - Disclosure - Leases - Schedule of the Maturities of Operating Lease Liabilities (Details)
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995877 - Disclosure - Leases - Schedule of the Maturities of Operating Lease Liabilities (Details) 2
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995887 - Disclosure - Leases - Additional Information (Details)
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995897 - Disclosure - Note Payable - Schedule of Notes Payable (Details)
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995907 - Disclosure - Note Payable - Additional Information (Details)
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995917 - Disclosure - Note Payable - Schedule Principal Installments Due (Details)
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995927 - Disclosure - Stockholders' Equity - Additional Information (Details)
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995937 - Disclosure - Stock Compensation - Additional Information (Details)
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995947 - Disclosure - Stock Compensation - Summary of Company's Equity Plans (Details)
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995957 - Disclosure - Stock Compensation - Summary of Share-based Compensation Arrangements by Share-based Payment Award (Details)
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995967 - Disclosure - Stock Compensation - Summary of Share-based Payment Arrangement, Expensed and Capitalized, Amount (Details)
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995977 - Disclosure - Stock Compensation - Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions (Details)
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995987 - Disclosure - Stock Compensation - Summary of Share-based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity (Details)
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995997 - Disclosure - Employee Benefit Plans - Additional Information (Details)
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996007 - Disclosure - Licenses and Collaborations - Additional Information (Details)
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996017 - Disclosure - Income Taxes - Schedule of Income (Loss) Before Provision for Income Taxes (Details)
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996027 - Disclosure - Income Taxes - Schedule of Components of Income Taxes Paid Net of Refunds (Details)
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996037 - Disclosure - Income Taxes - Schedule of Reconciliation of Provision for Income Taxes (Details)
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996047 - Disclosure - Income Taxes - Schedule of Reconciliation of Provision for Income Taxes (Details) 2
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996057 - Disclosure - Income Taxes - Additional Information (Details)
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996067 - Disclosure - Income Taxes - Summary of Deferred Tax Assets and Liabilities (Details)
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996077 - Disclosure - Income Taxes - Summary of Change in the Valuation Allowance (Details)
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996087 - Disclosure - Income Taxes - Summary of Activity Relating to Gross Amount of Unrecognized Tax Benefits (Details)
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996097 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996107 - Disclosure - Restructuring and Related Activities - Additional Information (Details)
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996127 - Disclosure - Related Party Transactions (Additional Information) (Details)
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996137 - Disclosure - Segment Reporting - Additional Information (Details)
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996147 - Disclosure - Segment Reporting - Schedule of Segment Operating Expenses Including Segment Expenses, and Net Loss (Details)
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996157 - Disclosure - Segment Reporting - Schedule of Segment Operating Expenses Including Segment Expenses, and Net Loss (Parenthetical) (Details)
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996167 - Disclosure - Segment Reporting - Schedule of Reportable Segment Assets (Details)
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Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Vested
Total asset acquisition cost
Acquisition cost
Business Combination, Acquisition-Related Cost, Expense
Segments [Domain]
Foreign
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Ending balance
Beginning balance
Restructuring liability
Restructuring Reserve
Restructuring Reserve, Total
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued, Total
Preferred Stock, Shares Issued
Preferred stock shares issued
Effective Income Tax Rate Reconciliation, Tax Credit, Amount [Abstract]
Tax credits:
Allocation to noncurrent deferred finance cost
Amount of Allocation To Noncurrent Deferred Finance Cost
Amount of allocation to noncurrent deferred finance cost.
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Due within one year
Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, Year One
Plan Name [Axis]
Plan Name
Payment of Deferred Issuance Costs Related to Unfunded Loan Commitments
Payment of deferred issuance costs related to unfunded loan commitments
Payment of deferred issuance costs related to unfunded loan commitments
Grantee Status [Domain]
Grantee Status
Entity Current Reporting Status
Entity Current Reporting Status
US Government Agencies Debt Securities [Member]
US Government Agencies Debt Securities [Member]
Operating Expenses [Abstract]
Operating expenses:
Level 2
Fair Value, Inputs, Level 2 [Member]
Total deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Two Thousand and Twenty One Employee Stock Purchase Plan [Member]
Two thousand and twenty one employee stock purchase plan.
2021 Employee Stock Purchase Plan [Member]
Common stock, shares authorized
Common Stock, Shares Authorized
MASSACHUSETTS
Massachusetts [Member]
Market Capitalization Threshold Amount Invalidating the Loan Coverage Ratio
Market capitalization threshold amount which invalidates loan coverage ratio upon condition.
Market capitalization threshold amount invalidating the loan coverage ratio
Income Tax Uncertainties [Abstract]
Product and Service [Axis]
Document Fiscal Period Focus
Document Fiscal Period Focus
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Debt Instrument, Interest Rate, Stated Percentage
Nominal interest rate
Entity Shell Company
Entity Shell Company
Grantee Status [Axis]
Grantee Status
Other Accrued Liabilities, Current
Other
Ares Agreement Member
Ares Agreement [Member]
Ares Agreement [Member]
Future lease payment
Operating Leases Future Minimum Payment Due
Operating leases future minimum payment due.
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalent
Cash and cash equivalents
Schedule Principal Installments Due
Schedule of Maturities of Long-Term Debt [Table Text Block]
Share based compensation arrangement by share based payment award minimum employee subscription rate.
Share Based Compensation Arrangement By Share Based Payment Award Minimum Employee Subscription Rate
Share purchases funded through payroll deductions for employee's eligible minimum annual compensation, percentage
Valuation Allowance [Line Items]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, Shares issued
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Asset Class [Domain]
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions [Line Items]
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions [Line Items]
Statement [Table]
Statement [Table]
Proceeds from borrowings, net of costs
Proceeds from borrowings, net of costs.
NEW JERSEY
New Jersey [Member]
Additions based on tax positions related to current year
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Addition to right-of-use assets obtained from operating lease liabilities
Temporary equity stock shares issued during the period shares.
Temporary Equity Stock Shares Issued During the Period Shares
Initial fee paid as consideration
Interest Receivable
Interest income receivable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Share based compensation arrangement by share based payment award, Options granted in period, Weighted average grant date fair value
Deferred Tax Asset, Valuation Allowance [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock Percent of Fair Market Value
Statement [Line Items]
Statement [Line Items]
Entity Filer Category
Entity Filer Category
Liabilities and Equity
Total liabilities and stockholders' equity
Debt Instrument Line Items
Debt Instrument [Line Items]
Effective Income Tax Rate Reconciliation, Tax Contingency, Percent
Effective Income Tax Rate Reconciliation, Tax Contingency, Percent, Total
Worldwide changes in unrecognized tax benefits, Percent
Payments to Acquire Marketable Securities
Purchase of marketable securities
Long-Term Debt, Maturity, Year Three
2028
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted-Average Exercise Price, Options exercisable
Restructuring Type [Axis]
Restructuring Type
Operating Loss Carryforwards [Table]
Amount Of Allocation To Discount On Note Payable
Amount of allocation to discount on note payable.
Reduction to the net carrying amount
Estimated Fair Value
Cash Equivalent And Marketable Securities
Cash equivalent and marketable securities.
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Cash and Cash Equivalents, Fair Value Disclosure
Cash and Cash Equivalents
License And Collaborations.
License And Collaborations [Text Block]
Licenses and Collaborations
Less: valuation allowance
Less: valuation allowance
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Deferred Tax Assets, Valuation Allowance, Total
Beginning balance
Ending balance
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Tax at U.S. statutory rate on income before income taxes, Percent
Cybersecurity Risk Management Third Party Engaged [Flag]
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Provision for income taxes, percent
Effective Income Tax Rate Reconciliation, Percent
Investment Income, Interest
Interest income
Income Tax Jurisdiction [Axis]
One Month CME Term Secured Overnight Financing Rate [Member]
One month CME term secured overnight financing rate.
1-Month CME Term SOFR [Member]
Loan facility.
Loan Facility [Member]
Loan Facility [Member]
Accrued Clinical Trial and Drug Manufacturing Expenses
Accrued clinical trial and drug manufacturing expenses.
Accrued drug manufacturing costs
Cash And Cash Equivalents And Marketable Securities
Cash And Cash Equivalents And Marketable Securities
Cash and cash equivalents and marketable securities
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table Text Block]
Schedule of Segment Operating Expenses Including Segment Expenses, and Net Loss
Segment, Expenditure, Addition to Long-Lived Assets
Expenditures for additions to long-lived assets
Prepaid expenses and other assets, noncurrent
Prepaid Expense and Other Assets, Noncurrent
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock
Additional paid-in capital
Fixed assets
Deferred Tax Assets, Property, Plant and Equipment
Related Party [Member]
Related Party [Member]
Percentage Of Exit Fee On Old Debt Principal Amount
Percentage Of Exit Fee On Old Debt Principal Amount
Percentage of exit fee on old debt principal amount
Vesting [Domain]
Number of options, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Issuance of common stock pursuant to exercise of options
Cybersecurity Risk Management, Strategy, and Governance [Table]
Unvested restricted stock awards
Unvested Restricted Stock Awards [Member]
Unvested Restricted Stock Awards
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount [Abstract]
Nontaxzable or nondeductible items:
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share attributable to common stockholders, basic
Summary of Company's Equity Plans
Schedule of Share-Based Compensation, Employee Stock Purchase Plan, Activity [Table Text Block]
Retirement Benefits [Text Block]
Employee Benefit Plans
Other Comprehensive Income (Loss), before Tax [Abstract]
Other comprehensive loss:
Debt Issuance Costs Paid To Creditors
Debt issuance costs paid to creditors.
Debt issuance costs paid to creditors
Number of Options, Beginning
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Options, Ending
Share based compensation by share based payment options non vested forfeitures in period weighted average exercise price.
Share Based Compensation By Share Based Payment Options Non Vested Forfeitures In Period Weighted Average Exercise Price
Weighted-Average Exercise Price, Cancelled and forfeited
Pnai Member
PNAI [Member]
PNAI [Member]
Revolving Credit Facility [Member]
Revolving Credit Facility [Member]
Liabilities, Current
Total current liabilities
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Issuance of common stock from underwritten follow-on offering, net of offering costs shares
Issuance Of Common Stock From Underwritten Follow On Offering Net Of Offering Costs Shares
Issuance of common stock from underwritten follow-on offering, net of offering costs
Federal [Member]
Domestic Tax Jurisdiction [Member]
Prepaid professionals services.
Prepaid professional services fees
Prepaid Professionals Services
Effective Income Tax Rate Reconciliation, Tax Credit, Percent [Abstract]
Tax credits:
Additions based on tax positions related to prior year
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Proceeds From Short Swing Profits
Proceeds from short swing profits.
Proceeds from short swing profits
Consolidation Items [Domain]
Equity, Attributable to Parent [Abstract]
Stockholders' equity
Entity Small Business
Entity Small Business
Increase (Decrease) in Accrued Liabilities, Total
Increase (Decrease) in Accrued Liabilities
Accrued and other liabilities
Abandonment Axis
Abandonment [Axis]
Abandonment
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Stock based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
2036 [Member]
Tax Year 2036 [Member]
Tax year 2036.
Other Commitments [Line Items]
Other Commitments [Line Items]
Nature of Operations [Text Block]
Organization and Description of the Business
Summary of Non-marketable Equity Securities
Debt Securities, Trading, and Equity Securities, FV-NI [Table Text Block]
Preferred Stock [Member]
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Non revolving credit facility.
Non Revolving Credit Facility [Member]
Non Revolving Credit Facility [Member]
Sale of Stock, Price Per Share
Sale of stock, price per share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Share based compensation arrangement by share based payment award, Options exercised in period, Total intrinsic value
Temporary equity purchase price per share
Temporary Equity Issue Price Per Share.
Temporary Equity Issue Price Per Share
Temporary equity purchase price per share
Share-Based Payment Arrangement [Text Block]
Stock Compensation
Two Thousand And Seventeen And Two Thousand And Twenty One Amended Equity incentive Plan.
Two Thousand And Seventeen And Two Thousand And Twenty One Amended Equity incentive Plan [Member]
2021 and 2017 Amended Equity Incentive Plan [Member]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Leases [Abstract]
Common Class A [Member]
Common Class A [Member]
Lessee, Lease, Description [Line Items]
Amendment Flag
Amendment Flag
LIBOR [Member]
London Interbank Offered Rate [Member]
London Interbank Offered Rate Member
Product and Service [Domain]
Maximum available capacity
Available Mutual Discretion
Available mutual discretion.
At statutory rate
Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount
Tax at U.S. statutory rate on income before income taxes
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share Attributable to Common Stockholders
Liabilities and Equity [Abstract]
Liabilities and stockholders' equity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Operating lease liabilities
Operating lease liabilities
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Common Stock [Member]
Common Stock [Member]
Cybersecurity Risk Role of Management [Text Block]
Tax credit carryforward amount
Tax Credit Carryforward, Amount
Employer contributions
Defined Contribution Plan, Employer Discretionary Contribution Amount
2026
Long-Term Debt, Maturity, Year One
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted-Average Exercise Price, Granted
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Liquidity covenant threshold amount
Liquidity Covenant Threshold Amount
Amount used as threshold in determining compliance with the liquidity covenant.
Collateralized note ,Amount
Secured Debt
Secured Debt, Total
Office and laboratory space at woborn massauchets.
Office and Laboratory Space at Woborn Massauchets [Member]
Office and Laboratory Space at Woborn Massauchets [Member]
Income Tax Paid, by Individual Jurisdiction [Line Items]
Prepaid Clinical Trial Costs
Prepaid clinical trial costs.
Prepaid clinical trial costs
Collateralized note , Effective interest rate
Debt Instrument, Interest Rate, Effective Percentage
Entity Address, Address Line One
Entity Address, Address Line One
Proceeds From Disgorgement Representing Short Swing Profits
Proceeds from disgorgement representing short swing profits.
Proceeds from disgorgement representing short swing profits
Deferred Tax Liabilities, Gross
Total gross DTL
Total gross deferred tax liabilities
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions
Marketable Securities [Table]
Marketable Securities [Table]
Fair Value Hierarchy and NAV [Axis]
Earnings Per Share Abstract
Earnings Per Share [Abstract]
Income Tax, Policy [Policy Text Block]
Income Taxes
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Foreign Currency Translations
Investment Type [Axis]
Investment Type
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Total gross DTA
Deferred Tax Assets, Gross
Total gross deferred tax assets
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Office and Laboratory Space at Brisbane California [Member]
Office and Laboratory Space at Brisbane California [Member]
Office and laboratory space at brisbane california.
Prepaid drug manufacturing costs
Prepaid Drug Manufacturing Costs
Prepaid drug manufacturing costs.
Document Type
Document Type
License and collaborations.
License and Collaborations [Table]
License And Collaborations [Table]
Income Taxes Paid, Net
Total income taxes paid
Entity Central Index Key
Entity Central Index Key
Summarizes the Unrealized Gains and Losses in Fair Value of the Company's Investments in Debt Securities
Debt Securities, Available-for-Sale [Table Text Block]
Commercial Planning Expenses
Commercial Planning Expenses
Commercial planning
Investments, Debt and Equity Securities [Abstract]
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Restructuring Reserve, Current
Restructuring liability, current
Restructuring lease liability
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net increase in cash and cash equivalents
Subsequent Event Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive Securities
Lessee Operating Lease Expiry Term
Lessee operating lease expiry term.
Lease expiring period
APIC, Share-Based Payment Arrangement, Option, Increase for Cost Recognition
Stock-based compensation
Common stock, par value
Common Stock, Par or Stated Value Per Share
Common stock, Par value
Money Market Funds, at Carrying Value
Money market funds
Related party transaction, expenses from transactions with related party
Operating Costs and Expenses
Operating Costs and Expenses, Total
Tranche D [Member]
Tranche D [Member]
Tranche D Member.
Share-Based Payment Arrangement, Tranche One [Member]
Tranche One [Member]
Reduction in the carrying amount of operating lease right-of-use assets
Operating Lease, Right-of-Use Asset, Periodic Reduction
2021 Equity Incentive Plan And 2017 Equity Incentive Plan [Member]
2021 Equity Incentive Plan And 2017 Equity Incentive Plan.
2021 EIP and 2017 EIP [Member]
Base Rate [Member]
Base Rate [Member]
Weighted-Average Remaining Contractual Life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Expected volatility, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Debt Securities, Available-for-Sale, Amortized Cost, Total
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Debt Securities, Available-for-Sale, Total
Debt Securities, Available-for-Sale
Fair value of the debt securities
Estimated Fair Value
Unvested restricted stock units.
Unvested Restricted Stock Units [Member]
Unvested Restricted Stock Units
Event
Event [Axis]
Event
Total fair market value of outstanding company stock
Fair Market Value Of Outstanding Company Stock
Fair market value of outstanding company stock.
Document Financial Statement Error Correction [Flag]
Stock issued during the period pursuant to exercise of underwriter's option
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Number of Options, Exercised
Debt Disclosure Abstract
Debt Disclosure [Abstract]
Amount of debt available on achievements on milestones
Amount Of Debt Available On Achievements On milestones
Amount of debt available on achievements on milestones.
Supplemental Cash Flow Elements [Abstract]
Supplemental disclosure of cash flow information
Prepaid Software Costs
Prepaid Software Costs
Prepaid software costs
Marketable Securities
Marketable Securities
Marketable Securities, Total
Accrued expenses and other liabilities, current
Accrued Liabilities, Current
Total accrued expenses and other current liabilities
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Cowen and Company, LLC.
Cowen and Company, LLC [Member]
Cowen and Company, LLC [Member]
Company shares issued
Stock Issued During Period Shares Licensing Payments In Equity (value)
Stock Issued During Period Shares Licensing Payments In Equity (value)
Issuance of common stock for payment of licensing fees in equity, net of offering cost
Schedule of Other Supplemental Information Related to Operating Leases
Schedule of Other Supplemental Information Related to Operating Leases [Table Text Block]
Schedule of other supplemental information related to operating leases.
CALIFORNIA
California [Member]
Entity Address, State or Province
Entity Address, State or Province
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Unvested, Ending balance
Unvested, Beginning balance
Money Market Funds Maturities
Money Market Funds Maturities
Money Market Funds Maturities
Remaining capacity available
Line of Credit Facility, Remaining Borrowing Capacity
Transition from Emerging Growth Company and Smaller Reporting Company Status
Transition from Emerging Growth Company and Smaller Reporting Company Status [Policy Text Block]
Transition from Emerging Growth Company and Smaller Reporting Company Status [Policy Text Block]
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding
Preferred stock shares outstanding
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Common Stock, Capital Shares Reserved for Future Issuance
Common stock capital, Shares reserved for future issuance
Carrying value of non-marketable equity securities
Nonmarketable Equity Securities Carrying Value
Nonmarketable equity securities carrying value.
Tax Year 2037 [Member]
Tax year 2037.
2037 [Member]
Marketable Securities, Current
Marketable securities
William Turner [Member]
William Turner.
William Turner
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount
State income taxes, net of federal effect
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Share-based Payment Arrangement, Expensed and Capitalized, Amount
Other
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount
Stock issued during the period pursuant to exercise of underwriter's option
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock pursuant to exercise of options, value
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Summary of Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Tranche A [Member]
Tranche A.
Tranche A [Member]
Accrued Clinical Trial Cost
Accrued Clinical Trial Cost
Accrued clinical trial costs
Proceeds from Sale and Maturity of Marketable Securities
Proceeds from maturities of marketable securities
Subsequent Event [Member]
Marketable Securities, Policy [Policy Text Block]
Marketable Securities
Deferred Tax Assets, Tax Credit Carryforwards, Research
Capitalized research & development
Debt Issuance Costs Paid To Third Parties.
Debt issuance costs paid to third parties.
Debt issuance costs paid to third parties
Antidilutive Securities [Axis]
Antidilutive Securities
Operating Loss Carryforwards [Line Items]
Other Liability, Current, Related Party [Extensible Enumeration]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Vesting percentage
Summary of Significant Accounting Policies
Basis of Presentation and Significant Accounting Policies [Text Block]
Exit fees, debt issuance costs
Exit Fees, Debt Issuance Costs
The exit fees associated with debt issuance costs.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate Intrinsic Value, Vested and expected to vest
Leased Facilities Abandoned Member
Leased Facilities Abandoned [Member]
Leased Facilities Abandoned [Member]
Discounted Lease Related Restructuring Liability Member
Discounted Lease Related Restructuring Liability [Member]
Discounted Lease Related Restructuring Liability [Member]
State [Member]
State and Local Jurisdiction [Member]
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Cumulative net fair value loss
Cumulative net fair value loss
Equity Securities Without Readily Determinable Fair Value Net Cumulative Gain Loss
Equity securities without readily determinable fair value net cumulative gain loss.
Cash [Member]
Goodwill, Impairment Loss
Impairment loss on available-for-sale marketable securities
Cash and Cash Equivalents [Domain]
Cash and Cash Equivalents
Other Commitments [Table]
Other Commitments [Table]
Achievement of Specified Worldwide Aggregate Annual Net Sales Milestones [Member]
Achievement of Specified Worldwide Aggregate Annual Net Sales Milestones [Member]
Achievement of specified worldwide aggregate annual net sales milestones.
Preferred stock issued, value
Preferred Stock, Value, Issued
Collateralized note , Maturity
Debt Instrument, Maturity Date
Minimum [Member]
Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Operating Lease Cost Total
Operating lease cost total.
Total operating lease cost
Employee Severance And Other Employee Termination Member
Employee Severance And Other Employee Termination [Member]
Employee Severance And Other Employee Termination [Member]
Financial Instrument [Axis]
Financial Instrument
Assets, Current [Abstract]
Current assets:
Other financial statement information.
Other Financial Statement Information [Abstract]
Reconciliation of Operating Profit (Loss) from Segments to Consolidated [Table]
Common Class B [Member]
Common Class B [Member]
Segment Reporting [Abstract]
Tax Period [Domain]
Unrealized Gain (Loss) on Investments
Unrealized gain on marketable securities
Liabilities, Current [Abstract]
Current liabilities:
Restructuring and Related Activities Disclosure [Text Block]
Restructuring and Related Activities
Segment Reporting, Other Segment Item, Composition, Description
Other segment items composition description
Related Party Transactions [Abstract]
Shares, Outstanding
Ending Balance, shares
Beginning balance, shares
Schedule of Estimated Fair Value of Investments in Available-for-sale Marketable Debt Securities
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Sublease Income
Less: Sublease income
Two Thousand and Twenty Four Inducement Plan [Member]
Two thousand and twenty four inducement plan.
Two Thousand And Twenty Four Inducement Plan [Member]
2024 Inducement Plan [Member]
Operating loss carryforwards
Operating Loss Carryforwards
Operating Loss Carryforwards, Total
Other Income
Other (expense) income, net
Property Subject to or Available for Operating Lease [Axis]
Property Subject to or Available for Operating Lease
Lessee, Leases [Policy Text Block]
Leases
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Beginning Balance
Weighted Average Grant Date Fair Value, Ending Balance
Weighted Average Grant Date Fair Value, Beginning Balance
Weighted average Grant date fair value
Contingent Milestone Obligation Accrued
Contingent Milestone Obligation Accrued
Contingent milestone obligation accrued
General and Administrative Expense [Member]
General and Administrative [Member]
Operating Lease, Liability
Present value of operating lease liabilities
Total operating lease liabilities
Auditor Firm ID
Follow-on offering costs included in accounts payable
Follow-on Offering Costs Included in Accounts Payable
Follow-on offering costs included in accounts payable
Debt Instrument, Basis Spread on Variable Rate
Basis spread on variable rate
Unvested Stock Options And Restricted Stock Awards [Member]
Unvested Stock Options And Restricted Stock Awards [Member]
Unvested Stock Options And Restricted Stock Awards.
Issuance Of Common Stock From Underwritten Follow On Offering Net Of Offering Costs
Issuance of common stock from underwritten follow-on offering net of offering costs.
Issuance of common stock from underwritten follow-on offering, net of offering costs, value
Depreciation, Amortization and Accretion, Net, Total
Depreciation, Amortization and Accretion, Net
Depreciation and amortization
Long-Term Debt, Maturity, Year Two
2027
2021 Loan Agreement [Member]
Two Thousand Twenty One Loan Agreement [Member]
Two thousand twenty one loan agreement.
Agreement Axis
Agreement [Axis]
Agreement
Lessee, Lease, Description [Table]
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance, Percent
Accounting policies.
Accounting Policies [Table]
Accounting Policies [Table]
Percentage of original contractual exit fee on old debt
Percentage Of Original Contractual Exit Fee On Old Debt
Percentage of original contractual exit fee on old debt.
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted-average shares used in computing net loss per share attributable to common stockholders, basic
2032 [Member]
Tax Year 2032 [Member]
Tax year 2032.
Document Information [Line Items]
Document Information [Line Items]
Amplyx [Member]
Amplyx.
Amplyx [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value, Options exercisable
Series C [Member]
Series C [Member]
Series C Redeemable Convertible Preferred Stock
Series C Redeemable Convertible Preferred Stock [Member]
Schedule of Reconciliation of Provision for Income Taxes
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Segments [Axis]
Valuation Allowance [Abstract]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Deferred Tax Assets, Net [Abstract]
Subsequent Events [Text Block]
Subsequent Events
Prepayment Fee Percentage Year Three
Prepayment fee percentage year three.
Prepayment fee percentage year three
Net carrying amount of debt
Total
Long-Term Debt
Long-term debt
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Cash Equivalents and Marketable Securities [Member]
Cash equivalents and marketable securities.
Cash Equivalents And Marketable Securities [Member]
Collateralized note , variable
Debt Instrument, Interest Rate Terms
Variable Rate [Domain]
Research and other credits
Deferred Tax Asset, In-Process Research and Development
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount
Change in valuation allowance
Equity, Attributable to Parent
Ending Balance, Value
Beginning Balance, Value
Total stockholders' equity
Preferred stock par value
Preferred Stock, Par or Stated Value Per Share
Preferred stock par or stated value per share
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Statement of Stockholders' Equity [Abstract]
Share-Based Payment Arrangement, Tranche Two [Member]
Tranche Two [Member]
Type of Restructuring
Type of Restructuring [Domain]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
2030
Long-Term Debt, Maturity, Year Five
Unamortized issuance costs net of accrued exit fees
Unamortized Issuance Costs Net of Accrued Exit Fees
Unamortized issuance costs net of accrued exit fees.
Marketable Securities Disclosure Text Block
Marketable Securities Disclosure Text Block
Marketable Securities
Entity Address, Address Line Two
Disclosure of Share-Based Compensation Arrangements by Share-Based Payment Award [Table Text Block]
Summary of Share-based Compensation Arrangements by Share-based Payment Award
Debt Instrument, Name [Domain]
Other Assets, Current
Other
Long-Term Debt, Maturity, Year Four
2029
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Summary of Activity Relating to Gross Amount of Unrecognized Tax Benefits
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, Other Segment Item, Amount
Other segment items**
Plan Name [Domain]
Plan Name
Two Thousand Twenty Five Loan Agreement [Member]
Two thousand twenty five loan agreement.
2025 Loan Agreement [Member]
Recently Issued Accounting Pronouncements Not Yet Adopted
Recently Issued Accounting Pronouncements Not Yet Adopted [Policy Text Block]
Recently issued accounting pronouncements not yet adopted.
Credit Facility [Axis]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Tax Period [Axis]
Collateralized note 2023-12
Collateralized Note Two Thousand Twenty Three - Twelve [Member]
Collateralized note two thousand twenty three - twelve [Member]
Related and Nonrelated Parties [Axis]
Related Party
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Amount
Valuation Allowance Deferred Tax Asset Increase (Decrease) In Income Tax Expense Amount
Valuation allowance deferred tax asset increase (decrease) in income tax expense amount.
Change charged to income tax expense
Area of Real Estate Property
Area of real estate availed on lease
Entity Address, City or Town
Entity Address, City or Town
Stock Repurchased During Period, Shares
Repurchase of common stock, shares
Market Capitalization Threshold Amount Invalidating The Liquidity Covenant
Market capitalization threshold amount which invalidates liquidity covenant upon condition.
Market capitalization threshold amount invalidating liquidity covenant
Number of Reportable Segments
Number of reportable segments
Security Exchange Name
Security Exchange Name
Payment of License Fee
Payment of license fee.
Payment of VT-109 license fee
Credit Facility [Domain]
Payment of License Fee1
Payment of license fee1.
Payment of VT-109 license fee
Total long-term debt
Carrying amount of debt outstanding
Net carrying amount of debt
Long-Term Debt, Gross
Other, Percent
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Debt Securities, Available-for-Sale, Unrealized Gain (Loss)
Debt Securities, Available-for-Sale, Unrealized Gain (Loss), Total
Change in fair value on marketable securities
Collateralized debt instrument maturity date.
Collateralized Debt Instrument Maturity Date
Collateralized debt instrument maturity date.
Counterparty Name [Axis]
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before provision for income taxes
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of Options, Vested and expected to vest
Two Thousand and Twenty One Equity Incentive Plan [Member]
Two Thousand and Twenty One Equity Incentive Plan [Member]
2021 Equity Incentive Plan [Member]
2021 EIP [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested Options Forfeited, Number of Shares
Number of Options, Cancelled and forfeited
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Available for sale debt securities gross unrealized loss1.
Available for Sale Debt Securities Gross Unrealized Loss1
Unrealized Losses
Unrealized Losses
Share-Based Payment Arrangement, Employee [Member]
Employees [Member]
Stockholders' Equity Note [Abstract]
Stockholders' Equity Note [Abstract]
Other intangibles
Deferred Tax Assets, Goodwill and Intangible Assets
Restricted cash
Cash and cash equivalents
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash and cash equivalents, beginning of year
Cash and cash equivalents, end of year
Share-Based Payment Arrangement, Nonemployee [Member]
Nonemployees [Member]
Interest Paid, Excluding Capitalized Interest, Operating Activity
Cash paid for interest expense
Statistical Measurement [Domain]
Statistical Measurement
Employee Stock Purchase Plan Espp Member
Employee Stock Purchase Plan ESPP [Member]
Employee Stock Purchase Plan ESPP [Member]
Assets, Current
Total current assets
Share-based Payment Arrangement, Expense
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Restricted Cash [Member]
Restricted Cash [Member]
Restricted cash [Member]
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
ICFR Auditor Attestation Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of Options, Options exercisable
Immunoglobulin A Nephropathy [Member]
Immunoglobulin A nephropathy.
IgAN [Member]
Note Payable
Operating loss carryforwards expiration year
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year.
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units R S U [Member]
Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock [Member]
Percentage of shares of company common stock outstanding for increase in shares reserved for issuance under stock plan
Percentage Of Shares Of Company Common Stock Outstanding For Increase In Shares Reserved For Issuance Under Stock Plan
Potential increase in shares reserved for future issuance as percentage of outstanding share
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Vesting [Axis]
Class of Stock [Axis]
Class of Stock
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Follow-on Public Offering [Member]
Follow On Public Offering [Member]
Follow On Public Offering [Member]
Amplyx and Novartis [Member]
Amplyx and Novartis [Member]
Amplyx and Novartis member.
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Liabilities
Total liabilities
U.S. Government Bonds [Member]
US Government Debt Securities [Member]
Financial Instruments [Domain]
Financial Instruments
Base rent
Operating Lease, Lease Income, Lease Payments
Reserves and accruals
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Restricted Stock [Member]
Restricted Stock [Member]
Variable Rate [Axis]
Weighted-average shares used in computing net loss per share attributable to common stockholders, diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Entity File Number
Entity File Number
Cover
Cover [Abstract]
Expected volatility, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Unvested ESPP shares.
Unvested ESPP Shares
Unvested ESPP Shares [Member]
Other segment items*
Other Expenses
Current and Deferred Provision for Income Tax
Current and deferred provision for income taxes.
Current and deferred provision for income taxes
Prepaid expenses and other assets, current
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Total prepaid expenses and other current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Cancelled and forfeited
Cancelled and forfeited
Common Stock, Conversion Basis
Common stock conversion basis
Investments [Domain]
Investments
License and collaborations.
License and Collaborations [Line Items]
License And Collaborations [Line Items]
Summary of Valuation Allowance [Table Text Block]
Summary of Change in the Valuation Allowance
Prepayment fee percentage first two years
Prepayment Fee Percentage First Two Years
Prepayment fee percentage first two years.
Sale of Stock [Domain]
Sale of Stock
Segment Reporting Disclosure [Text Block]
Segment Reporting
General and Administrative Expense, Total
General and Administrative Expense
General and administrative
Achievement as Assumed Liabilities upon Acquisition [Member]
Achievement as assumed liabilities upon acquisition member.
Atacicept for IgAN [Member]
Atacicept for IgAN.
Atacicept for IgAN [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period
Number of shares issued under share based payment arrangement
License Issue Fees Amount
License issue fees amount.
Deferred Tax Assets, Other
Other deferred tax assets
Shares Reserved for ESPP Purchases [Member]
Shares reserved for ESPP purchases.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted-Average Exercise Price, Vested and expected to vest
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Pronouncements
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of the Maturities of Operating Lease Liabilities
Antidilutive Securities Excluded From Computation Of Earnings Per Share Line Items
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of Share-based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent
Other, Percent
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Share based compensation arrangement by share based payment award, Vesting period
Vesting period
Accretion Of Loan Exit Fee And Amortization Of Loan Costs
Accretion of loan exit fee and amortization of loan costs.
Accretion of loan exit fee and amortization of loan costs, net
Collaborative Arrangement Milestone Payable on Aggregate Annual Sales Net2
Collaborative Arrangement Milestone Payable on Aggregate Annual Sales Net2
Collaborative arrangement milestone payable on aggregate annual sales net2.
Percentage of Old Debt Exit Fee Waived in Connection With The Refinancing
Percentage of old debt exit fee waived in connection with the refinancing.
Percentage of old debt exit fee waived in connection with the refinancing
Risk-free rate, Minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Domestic
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract]
Common Stock Held by Non-Affiliates Exceeded
Common Stock Held by Non-Affiliates Exceeded
Common Stock Held by Non-Affiliates Exceeded
Proceeds from issuance of common stock in follow-on offerings
Proceeds From Issuance Of Common Stock Follow On Offering
Proceeds from issuance of common stock follow on offering.
Lessee, Operating Lease, Term of Contract
Operating lease term
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding
Common stock, Shares outstanding
Common stock, Shares outstanding
Operating Lease, Liability, Current
Operating lease liabilities
Less: Current portion of operating lease liabilities
Depreciation, Depletion and Amortization
Depreciation, Depletion and Amortization, Total
Depreciation and amortization
Cybersecurity Risk Management Processes Integrated [Flag]
Document Transition Report
Document Transition Report
Net deferred tax assets
Deferred Tax Assets, Net
Operating Expenses
Total operating expenses
Research and Development Expense, Total
Research and Development Expense
Research and development
Direct research and development
Lessee, Operating Leases [Text Block]
Leases
Payments for Repurchase of Common Stock
Repurchase of common stock
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest
Statement of Cash Flows [Abstract]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Stock based compensation, Percent
Equity [Text Block]
Stockholders' Equity
Prepayment of the loan
Line Of Credit Facility Percentage Prepayment Of Loan or Maturity Date is Not Extended
Line of credit facility percentage prepayment Of loan or maturity date is not extended.
Earnings Per Share [Text Block]
Net Loss Per Share Attributable to Common Stockholders
Deferred Tax Liabilities, Other
Other deferred tax liabilities
Cybersecurity Risk Management Processes Integrated [Text Block]
Net loss
Segment and consolidated net loss
Aggregate Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Operating Lease, Cost
Operating lease cost
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Dividend yield
Net Proceeds From Refinancing Under Loan and Security Agreement Net of Costs
Net proceeds from refinancing under loan and security agreement net of costs.
Proceeds from refinancing under loan and security agreement, net
Regulatory Approval In The U S [Member]
Regulatory Approval In The U.S [Member]
regulatory approval in the U.S.
Operating Lease, Payments
Cash paid for operating lease liabilities
Tranche E [Member]
Tranche E [Member]
Tranche E.
Assets [Abstract]
Assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expense and other current assets
Restructuring and Related Activities [Abstract]
Other Financial Statement Information.
Other Financial Statement Information [Text Block]
Other Financial Statement Information
Document Fiscal Year Focus
Document Fiscal Year Focus
Proceeds from sale of marketable securities
Proceeds From Sale of Marketable Securities
Proceeds from sale of marketable securities
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities
Retirement Benefits [Abstract]
Accounts Payable, Current, Total
Accounts Payable, Current
Accounts payable
Interest expense
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Schedule of Income (Loss) Before Provision for Income Taxes
Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]
Research and Development Expense [Member]
Research and Development [Member]
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Non-Marketable Equity Securities
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Schedule of Prepaid Expenses and Other Current Assets
Research [Member]
Research Tax Credit Carryforward [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Cost And Reserve [Line Items]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Common Stock Issued During Period Underwriters Option Shares
Common stock issued during period underwriters option shares.
Common stock issued pursuant to underwriters option shares
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Class A Common Stock Options Issued and Outstanding
Class A common stock issued and outstanding.
Class A Common Stock Issued And Outstanding [Member]
Term Loan [Member]
Term loan.
Term Loan [Member]
Payroll and related
Payroll and Related Expenses
Payroll and related expenses.
Vested but Unsettled Stock Units [Member]
Vested but Unsettled Stock Units [Member]
Vested but Unsettled Stock Units
Debt Instrument [Axis]
Yale License Agreement Member
Yale License Agreement [Member]
Yale License Agreement [Member]
Share-Based Payment Arrangement [Abstract]
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Share based compensation, Nonvested awards, Compensation cost not yet recognized Stock options and equity instruments other than options
Issuance of Series C redeemable convertible preferred stock, net of issuance cost of $389
Temporary Equity, Stock Issued During Period, Value, New Issues
Temporary equity shares issued during the period value
Sale of Stock [Axis]
Sale of Stock
Abandonment Domain
Abandonment [Domain]
Abandonment
Prepaid Commercial Costs
Prepaid commercial costs.
Prepaid commercial planning costs
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by (used in) investing activities
Title of 12(b) Security
Title of 12(b) Security
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount
Stock based compensation
Income Tax Paid, by Individual Jurisdiction [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Cancelled and Forfeited
Money Market Funds [Member]
Money Market Funds [Member]
Related and Nonrelated Parties [Domain]
Related Party
Income Taxes
Income Tax Disclosure [Text Block]
Schedule Of Accrued And Other Current Liabilities
Schedule Of Accrued And Other Current Liabilities [Table Text Block]
Schedule of Accrued Expenses And Other Current Liabilities
Lessor, Operating Lease, Payment to be Received
Sublease payment
Milestone payments paid.
Milestone Payments Paid
Milestone payments paid
Equipment Abondoned Member
Equipment Abondoned [Member]
Equipment Abandoned [Member]
Document Information [Table]
Document Information [Table]
Reconciliation of Revenue from Segments to Consolidated [Table]
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Stanford University [Member]
Stanford university.
Weighted-Average Exercise Price, Opening balance
Weighted-Average Exercise Price, Ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised, Total
Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised
Proceeds from exercise of stock options and employee stock purchase plan
Income Tax Disclosure [Abstract]
Debt issuance costs paid to noncurrent deferred financing costs
Debt Issuance Costs Paid To Third Parties Allocated To Noncurrent Deferred Financing Costs
Debt issuance costs paid to third parties allocated to noncurrent deferred financing costs.
Ending balance
Beginning balance
Unrecognized Tax Benefits
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Amount Withdrawn From The Loan Agrrement
Amount withdrawn from the loan agreement.
Amount withdrawn from the loan agreement
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Related Party Transaction [Table]
Collateralized note 2021-12
Collateralized Note Two Thousand Twenty One - Twelve [Member]
Collateralized note two thousand twenty one - twelve.
Risk-free rate, Maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Common stock capital shares minimum increase in shares reserved for future issuance.
Common Stock Capital Shares Minimum Increase In Shares Reserved For Future Issuance
Potential increase in shares reserved for future issuance (in shares)
Exercise Price of Repurchased Unvested Shares
Exercise Price of Repurchased Unvested Shares
Exercise price of repurchased unvested shares
Other Significant Items [Abstract]
Other significant items.
Other Significant Items:
Subsequent Event Type [Axis]
Valuation Allowance Deferred Tax Asset Increase (Decrease) Other Comprehensive Income (Loss) Amount
Valuation allowance deferred tax asset increase (decrease) other comprehensive income (loss) amount
Changes charged to other comprehensive income
Purchases of property and equipment included in accounts payable
Purchases of Property and Equipment Included in Accounts Payable
Purchases of property and equipment included in accounts payable
Employee-related Liabilities, Current, Total
Employee-related Liabilities, Current
Accrued payroll
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Licenses And Collaborations Abstract
Licenses And Collaborations [Abstract]
Entity Ex Transition Period
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total minimum lease payments
Future lease payment
Other than Temporary Impairment Losses, Investments
Impairment loss on available-for-sale marketable securities
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: Imputed interest
Federal research & development credits, Percent
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Federal research & development credits, Percent
Initial cost
Equity Securities Without Readily Determinable Fair Value Initial Cost
Equity securities without readily determinable fair value initial cost.
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Share purchases funded through payroll deductions for employee's eligible maximum annual compensation, percentage
Equity Components [Axis]
Equity Components
Tranche C Member.
Tranche C [Member]
Tranche C [Member]
Amplyx Agreement [Member]
Amplyx agreement member.
Amplyx Agreement [Member]
Deferred tax liabilities, right-of-use assets.
Deferred Tax Liabilities, Right-of-use Assets
Right of use
Right of use
Event
Event [Domain]
Event
Nonoperating Income (Expense)
Total other income, net
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions.
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions [Table]
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions [Table]
Equity Component [Domain]
Equity Component
Asset Class [Axis]
Achievement of Various Clinical Development and Regulatory Milestones [Member]
Achievement of various clinical development and regulatory milestones member.
Contract Manufacturing [Member]
Contract manufacturing.
Contract Manufacturing [Member]
Percentage Of Increase In Rent Annually
Percentage Of Increase In Rent Annually
Percentage of increase in rent annually
Reconciliation of Revenue from Segments to Consolidated [Table Text Block]
Schedule of Reportable Segment Assets
Class of Stock Disclosures [Abstract]
Variable lease cost
Variable Lease Cost and Refunds
Variable lease cost and refunds.
Document Annual Report
Agreement Domain
Agreement [Domain]
Agreement
Operating Lease, Liability, Statement of Financial Position [Extensible Enumeration]
Other assets
Other assets
Increase (Decrease) in Other Current Assets
Prepaid Insurance
Prepaid insurance
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures, Total
Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures
Issuance of common stock upon vesting of restricted stock units, shares
IPO [Member]
IPO [Member]
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock pursuant to employee stock purchase plan
Maximum number of shares authorized
Stock issued during period shares licensing payments in equity.
Stock Issued During Period Shares licensing Payments in Equity
Company shares issued
Issuance of common stock for payment of licensing fees, net of offering costs, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Expiration period
Effective Income Tax Rate Reconciliation, Tax Contingency, Amount
Effective Income Tax Rate Reconciliation, Tax Contingency, Amount, Total
Worldwide changes in unrecognized tax benefits
Federal net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Domestic
Reduction In Contingent Future Development
Reduction In Contingent Future Development
Reduction in contingent future development
Novartis [Member]
Novartis [Member]
Novartis [Member]
Maximum [Member]
Maximum [Member]
Accretion of Discount and Amortization of Premium on Purchase of Debt Securities
Accretion of discount and amortization of premium on purchase of debt securities.
Accretion of discount and amortization of premium on purchase of debt securities
Statistical Measurement [Axis]
Statistical Measurement
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted-Average Exercise Price, Exercised
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Class A common stock, $0.001 par value; 500,000,000 shares authorized as of December 31, 2025 and 2024; 71,267,429 and 63,559,858 shares issued and outstanding as of December 31, 2025 and 2024, respectively
Line of credit exit fee percentage
Line of Credit Exit Fee Percentage
The percentage of exit fee payable on the aggregate principal amount of loan, in the event of default or prepayment.
Deferred tax assets, lease liability.
Deferred Tax Assets, Lease Liability
Lease liability
Due after one year to two years
Available For Sale Securities Debt Maturities After One Through Two Years Fair Value
Available for sale securities debt maturities after one through two years fair value.
Collaborative Arrangement Milestone Payable on Aggregate Annual Sales Net1
Collaborative arrangement milestone payable on aggregate annual sales net1.
Collaborative Arrangement Milestone Payable on Aggregate Annual Sales Net1
Unvested stock options and restricted stock unit.
Unvested Stock Options And Restricted Stock Unit [Member]
Unvested Stock Options And Restricted Stock Unit [Member]
Deferred Tax Assets, Operating Loss Carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Federal and state net operating loss carryforward
Ares Trading S A Member
Ares Trading S A [Member]
Ares Trading S A [Member]
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Tax Credit Carryforward [Axis]
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State income taxes, net of federal effect, Percent
Marketable Securities [Line Items]
Marketable Securities [Line Items]
Entity Public Float
Entity Public Float
Preferred Stock, Shares Authorized
Preferred stock shares authorized
Two thousand twenty two ATM facility.
Two Thousand Twenty Two ATM facility [Member]
2022 ATM facility [Member]
Schedule of Notes Payable
Schedule of Debt [Table Text Block]
Follow-on Offering Costs Included in Accrued and Other Liabilities
Follow-on offering costs included in accrued and other liabilities
Follow-on offering costs included in accrued and other liabilities
Total marketable securities
Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Fair Value
Employee Stock Purchase Plan [Member]
Employee Stock [Member]
Entity Registrant Name
Entity Registrant Name
Interest or penalty accruals associated with uncertain tax benefits
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued
Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued, Total
Schedule of Components of Income Taxes Paid Net of Refunds [TableTextBlock]
Tabular disclosure of the components of income tax paid net of refunds.
Schedule of Components of Income Taxes Paid Net of Refunds
Entity Voluntary Filers
Entity Voluntary Filers
Debt facility payments description
Line of Credit Facility, Frequency of Payments
Conversion of Stock, Shares Issued
Conversion of redeemable convertible preferred stock to common stock
Subsequent Events [Abstract]
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
SOFR [Member]
Secured Overnight Financing Rate (SOFR) Overnight Index Swap Rate [Member]
Share based Compensation Arrangement By Share based Payment Award Restricted Shares Of Fully Issued And Outstanding Common Stock
Share based Compensation Arrangement By Share based Payment Award Restricted Shares Of Fully Issued And Outstanding Common Stock
Share based compensation arrangement by share based payment award, Restricted shares of fully issued and outstanding common stock
Provision for income taxes
Income Tax Expense (Benefit)
Provision for income taxes
Income tax provision
Provision for income taxes
Provision for income taxes
Stock Repurchased During Period, Value
Repurchase of common stock
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Collateralized Note Two Thousand Twenty Five - Zero Six [Member]
Collateralized Note Two Thousand Twenty Five - Zero Six Member
Collateralized note 2025-06
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentrations of Credit Risk and Other Risks and Uncertainties
Deferred Offering Costs .
Deferred Offering Costs [Policy Text Block]
Deferred Offering Costs
Debt instrument threshold amount invalidating liquidity covenant.
Debt Instrument Threshold Amount Invalidating Liquidity Covenant
Debt instrument threshold amount which invalidates liquidity covenant upon condition.
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive income
Consolidation Items [Axis]
2017 Equity Incentive Plan [Member]
2017 Equity Incentive Plan.
2017 EIP [Member]
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Purchase of property and equipment
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Granted
Debt principal balance of collateralized note
Debt Principal Balance Of Collateralized Note
Debt principal balance of collateralized note.
Percentage Of Prepayment Fee On Old Debt Waived In Connection With The Refinancing
Percentage of prepayment fee on old debt waived in connection with the refinancing.
Percentage of prepayment fee
Assets
Total assets
U.S. State and Local:
Income Tax Paid, State and Local, after Refund Received
Income Tax Paid, State and Local, after Refund Received, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Life, Options exercisable
Income Statement [Abstract]
Restructuring Cost [Table]
Schedule Of Restructuring And Related Costs [Table]
Collaborative Arrangement Aggregate Annual Sales Net Threshold Amount For Event Achievement Two
Collaborative arrangement aggregate annual sales net threshold amount for event achievement two.
Collaborative arrangement aggregate annual sales net threshold 2
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Cash, Cash Equivalent, and Marketable Security [Text Block]
Cash, Cash Equivalents, and Marketable Securities
Debt Issuance costs paid to third parties allocated to other nonoperating expense
Debt Issuance Costs Paid To Third Parties Allocated To Other Nonoperating Expense
Debt Issuance costs paid to third parties allocated to other nonoperating expense.
Accrued commercial expenses
Accrued Commercial Expenses Current
Carrying value as of the balance sheet date of obligations incurred through that date and payable for commercial expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Stock shares issued during the period new issues shares
Stock Issued During Period, Shares, New Issues
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Vested
Property Subject to or Available for Operating Lease [Domain]
Property Subject to or Available for Operating Lease
Milestone payments payable.
Milestone Payments Payable
Milestone payments payable
Conversion of redeemable preferred stock into common stock
Conversion Of Redeemable Preferred Stock Into Common Stock [Member]
Conversion Of Redeemable Preferred Stock Into Common Stock [Member]
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share attributable to common stockholders, diluted
Operating Segments [Member]
Operating Segments [Member]
Effective Income Tax Rate Reconciliation, Percent [Abstract]
City Area Code
City Area Code
Auditor Name
Line Of Credit Facility Percentage Prepayment Of Loan or Maturity Date is Extended
Line Of Credit Facility Percentage Prepayment Of Loan or Maturity Date is Extended
Extended maturity date
Proceeds from line of credit
Proceeds from Lines of Credit
Proceeds from Lines of Credit, Total
Maximum available capacity
Debt Instrument, Face Amount
Revolving credit facility with borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
Unvested Shares Repurchased
Unvested Shares Repurchased
Unvested shares repurchased
Collaborative Arrangement Aggregate Annual Sales Net Threshold Amount For Event Achievement One
Collaborative arrangement aggregate annual sales net threshold amount for event achievement one.
Collaborative arrangement aggregate annual sales net threshold 1
Counterparty Name [Domain]
Federal research & development credits
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount
Federal research & development credits
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock pursuant to employee stock purchase plan, value
Dividends, Cash, Total
Dividends, Cash
Cash dividends
Two Thousand And Seventeen EIP, Two Thousand And Twenty One EIP And Two Thousand And Twenty Four Inducement Plan[Member]
Two Thousand And Seventeen EIP, Two Thousand And Twenty One EIP And Two Thousand And Twenty Four Inducement Plan.
2017 EIP, 2021 EIP And 2024 Inducement Plan [Member]
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term
Stockholders' Equity Note, Stock Split, Conversion Ratio
Stock split ratio
Lease, Cost
Net lease cost
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Property, Plant and Equipment, Net, Total
Property, Plant and Equipment, Net
Property and equipment, net
Cash Equivalents And Marketable Securities [Abstract]
Cash equivalents and marketable securities abstract.
Operating Income (Loss)
Loss from operations
Loss from operations
Loss from operations
Two Thousand And Seventeen Equity incentive Plan [Member]
Two thousand and seventeen equity incentive plan.
2017 Equity Incentive Plan [Member]
Retained Earnings [Member]
Accumulated Deficit [Member]
Clinical Trials [Member]
Clinical trials.
Clinical Trials [Member]
Cash and Cash Equivalents [Axis]
Cash and Cash Equivalents
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation
Payment of cost and underwriting discounts and commissions related to follow-on
Payments of Stock Issuance Costs on Follow on Offering
Payments of stock issuance costs on follow on offering.
Payment of issuance costs and underwriting fees related to follow-on offerings
Proceeds from Short Swing Settlement
Proceeds from short swing settlement.
Proceeds from short swing settlement
Operating Lease, Weighted Average Discount Rate, Percent
Weighted-average discount rate for operating leases
Operating Lease, Liability, Noncurrent
Operating lease liabilities, noncurrent
Non-current operating lease liabilities
Level 1
Fair Value, Inputs, Level 1 [Member]
Class of Stock [Line Items]
Class Of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Notes Payable
Total borrowings
Lease, Cost [Table Text Block]
Schedule of Lease Cost
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent [Abstract]
Nontaxzable or nondeductible items:
Auditor Location
Nonoperating Income (Expense) [Abstract]
Other income (expense):
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Summary of Dilutive Shares Excluded From Computation of Diluted Net Loss Per Share
Corporate Debt Securities [Member]
Corporate Debt Securities [Member]
Income Tax Jurisdiction [Domain]
Entity Interactive Data Current
Entity Interactive Data Current
Statement of Income Location, Balance [Domain]
Income Statement Location
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities
Segment Reporting, Revenue Reconciling Item [Line Items]
ORGANIZATION AND DESCRIPTION OF THE BUSINESS [Table]
ORGANIZATION AND DESCRIPTION OF THE BUSINESS [Table]
Tranche B [Member]
Tranche B [Member]
Tranche B.
Line of Credit Facility, Current Borrowing Capacity
Additional borrowing capacity
Entity Tax Identification Number
Entity Tax Identification Number
Two thousand and seventeen eip and two thousand and twenty one eip.
Two Thousand And Seventeen EIP And Two Thousand And Twenty One EIP [Member]
2017 EIP And 2021 EIP [Member]
Accounting policies.
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Achievement Of Specified Bla Filing Or Regulatory Approval Milestones Member
Achievement Of Specified BLA Filing Or Regulatory Approval Milestones [Member]
Achievement Of Specified BLA Filing Or Regulatory Approval Milestones [Member]
Local Phone Number
Local Phone Number
Debt Securities, Available-for-Sale, Unrealized Gain
Unrealized Gains
Related party payable
Other Liabilities, Current
Auditor Opinion [Text Block]
Auditor Opinion
Collateralized note 2022-11
Collateralized Note Two Thousand Twenty Two - Eleven [Member]
Collateralized note two thousand twenty two - eleven [Member]
Accounting Policies [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Cash and Cash Equivalents [Member]
Cash and cash equivalents [Member]
Class of Stock [Domain]
Class of Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Share-based compensation arrangement by share-based payment award, Number of shares available for issuance
Shares available for future issuance
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Share based compensation, Nonvested awards, Compensation cost not yet recognized period of recognition stock options and equity instruments other than options
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Life, Vested and expected to vest
Tax Credit Carryforward, Name [Domain]