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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Licenses and Collaborations - Additional Information (Detail) - USD ($) $ in Thousands		9 Months Ended	12 Months Ended
	Oct. 31, 2020	Sep. 30, 2022	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
License And Collaborations [Line Items]
Research and development			$ 78,225	$ 68,993
Ares Agreement [Member] \| Ares Trading S A [Member]
License And Collaborations [Line Items]
Temporary equity shares issued during the period value	$ 13,100
Milestone payments payable						$ 25,000
Related party transaction, expenses from transactions with related party			2,800	$ 4,500
Ares Agreement [Member] \| Ares Trading S A [Member] \| Achievement Of Specified BLA Filing Or Regulatory Approval Milestones [Member]
License And Collaborations [Line Items]
Milestone payments payable						$ 176,500
Ares Agreement [Member] \| Ares Trading S A [Member] \| Achievement Of Specified Commercial Milestones [Member]
License And Collaborations [Line Items]
Milestone payments payable							$ 515,000
Amplyx Agreement [Member]
License And Collaborations [Line Items]
Milestone payments payable					$ 2,000
Acquisition cost					5,000
Research and development		$ 3,700			7,000
Reduction in contingent future development		7,000
Contingent milestone obligation accrued					$ 2,000
Company shares issued		$ 5,700
Amplyx Agreement [Member] \| Amplyx and Novartis [Member] \| Achievement of Various Clinical Development and Regulatory Milestones [Member]
License And Collaborations [Line Items]
Milestone payments payable			7,000
Novartis [Member] \| Amplyx and Novartis [Member] \| Achievement of Various Clinical Development and Regulatory Milestones [Member]
License And Collaborations [Line Items]
Milestone payments payable			$ 62,000
Common Class A [Member]
License And Collaborations [Line Items]
Issuance of common stock for payment of licensing fees, net of offering costs, shares		283,034		283,034
Common Class A [Member] \| IPO [Member]
License And Collaborations [Line Items]
Conversion of redeemable convertible preferred stock to common stock	1,913,501