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Condensed Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities    
Net loss $ (89,056) $ (32,609)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation, amortization and accretion (846) 176
Reduction in the carrying amount of operating lease right of use assets 2,271 0
Stock-based compensation 8,887 3,012
Issuance of Class A common stock for licensing payment, net of costs 3,592 0
Payment for MAU868 asset purchase 0 5,000
Restructuring payments 0 (999)
Gain on sale of PNAi technology 0 (2,691)
Change in fair value of non-marketable equity securities 809 892
Changes in operating assets and liabilities:    
Prepaid expense and other current assets (8,182) (2,306)
Other assets (111) (51)
Accounts payable 10,606 475
Accrued and other current liabilities 7,036 5,393
Operating lease liabilities (2,602) 0
Net cash used in operating activities (67,596) (23,708)
Cash flows from investing activities    
Proceeds from sale of PNAi technology 0 796
Payment for MAU868 asset purchase 0 (5,000)
Purchase of property and equipment (62) 0
Purchase of marketable securities (148,490) 0
Proceeds from maturities of marketable securities 78,000 0
Net cash used in investing activities (70,552) (4,204)
Cash flows from financing activities    
Proceeds from exercise of stock options and employee stock purchase plan 2,083 550
Proceeds from issuance of Class A common stock upon initial public offering, net of underwriting discounts and commissions 0 51,176
Proceeds from borrowings, net of costs 19,816 4,921
Payment of offering costs related to initial public offering 0 (2,765)
Proceeds from issuance of Class A common stock in follow-on offering 86,131 0
Payment of costs and underwriting discounts and commissions related to follow-on offering (6,097) 0
Net cash provided by financing activities 101,933 53,882
Net (decrease) increase in cash and cash equivalents and restricted cash (36,215) 25,970
Cash, cash equivalents and restricted cash, beginning of year 79,967 53,997
Cash, cash equivalents and restricted cash, end of year 43,752 79,967
Supplemental disclosure of cash flow information    
Cash paid for interest 895 17
Cash paid for operating leases 2,734 0
Issuance of Class A common stock in payment of licensing fees 2,000 0
Reclassification of redeemable convertible preferred stock into common stock upon initial public offering 0 139,576
Non-marketable equity securities received as partial proceeds from sale of PNAi technology 0 1,759
Lease assignment 0 136
Liability assumed in connection with MAU868 asset purchase 0 2,000
Cash and cash equivalents [Member]    
Cash flows from financing activities    
Cash, cash equivalents and restricted cash, beginning of year 79,674  
Cash, cash equivalents and restricted cash, end of year 43,459 79,674
Restricted cash [Member]    
Cash flows from financing activities    
Cash, cash equivalents and restricted cash, beginning of year 293  
Cash, cash equivalents and restricted cash, end of year $ 293 $ 293