Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Statement of Cash Flows [Abstract]
Net Loss	$ (92,014)	$ (175,105)
Adjustments to reconcile net loss to net cash used in operating activities:
Non-cash share consideration, issued in acquisition of IPR&D	0	9,415
Non-cash operating lease expense (benefit)	354	(76)
Depreciation expense	689	278
Share based compensation expense	13,936	5,285
Amortization of discounts on investments, net	(481)	0
Unrealized foreign currency transaction gain, net	(1,375)	(56)
Changes in operating assets and liabilities:
Decrease (increase) in prepaid expenses and other current assets	4,794	(3,801)
(Increase) decrease in other receivable	(1,244)	14,216
Decrease in other non-current assets	11	2
Decrease in accounts payable	(1,091)	(2,690)
Increase in accrued expenses	8,197	11,568
(Decrease) increase in other current liabilities	(248)	1,434
Increase in withholding tax payable	0	5,957
Net cash used in operating activities	(68,472)	(133,573)
Cash flows from investing activities:
Purchase of property and equipment	(1,610)	(159)
Purchase of marketable securities	(260,367)	0
Sales and redemption of marketable securities	181,780	0
Net cash used for investing activities	(80,197)	(159)
Cash flows from financing activities:
Proceeds from exercise of share options	1,710	5,309
Proceeds from issuance of redeemable convertible preferred shares	0	3,000
Issuance costs related to redeemable convertible preferred shares	0	(60)
Net cash provided by financing activities	1,710	8,249
Effect of exchange rate changes on cash and cash equivalents	(2,291)	148
Net decrease in cash, cash equivalents and restricted cash	(149,250)	(125,335)
Cash and cash equivalents, and restricted cash—beginning of period	248,182	254,350
Cash and cash equivalents, and restricted cash—ending of period	98,932	129,015
Cash and cash equivalents—end of period	78,862	109,015
Restricted cash—end of period	20,070	20,000
Cash and cash equivalents, and restricted cash—ending of period	98,932	129,015
Supplemental disclosure of cash information
Cash paid for income taxes	523	0
Supplemental disclosure of non-cash operating activities:
Right-of-use assets obtained in exchange for lease obligations	1,233	247
Issuance costs in accounts payable and other accrued liabilities	0	3,310
Purchase of property and equipment in accounts payable	$ 551	$ 0