144 0001830755 XXXXXXXX LIVE 0000879407 Arrowhead 001-38042 177 East Colorado Blvd Suite 700 Pasadena CA 91105 6266964702 James Hamilton Officer Common Merrill Lynch

75 Rockefeller Plz Flr 2 New York NY 10019

39728 2506627.22 135809558 01/05/2026 NASDAQ Common 01/01/2022 Compensation Issuer N 55000 01/01/2022 Compensation Common 01/04/2023 Compensation Issuer N 60000 01/04/2023 Compensation Common 01/04/2024 Compensation Issuer N 75000 01/04/2024 Compensation Common 01/04/2025 Compensation Issuer N 100000 01/04/2025 Compensation Y 01/05/2026 09/03/2025 James Hamilton