Share-based compensation (Tables)

12 Months Ended

Dec. 31, 2021

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Changes in Unvested Ordinary Shares

A summary of the changes in the Company’s unvested ordinary shares from December 31, 2019 through December 31, 2021 are as follows:

	Number of			Weighted
	unvested			average
	ordinary			grant date
	shares			fair value
Unvested ordinary shares as of December 31, 2019		1,727,874		$	2.96
Granted		1,993,503		$	7.58
Vested		(746,095	)	$	3.44
Forfeited		(137,790	)	$	3.46
Unvested ordinary shares as of December 31, 2020		2,837,492		$	6.38
Granted		—			—
Vested		(916,172	)	$	5.61
Forfeited		(18,262	)	$	6.80
Unvested ordinary shares as of December 31, 2021		1,903,058		$	6.43

Summary of Share Options Activity

The following table summarizes the Company’s share options activity for the year ended December 31, 2021:

Summary of Weighted-Average Assumptions Used in Black-Scholes Option Pricing Model

The weighted-average assumptions used in the Black-Scholes option pricing model to determine the fair value of the share options granted to employees during the year ended December 31, 2021 and 2020 were as follows:

	Year Ended December 31,			Year Ended December 31,
	2021			2020
Expected term (in years)	6.02 Years			3.21 Years
Expected volatility		72.15	%		73.81	%
Expected dividend yield		0.00	%		0.00	%
Risk free interest rate		1.07	%		0.20	%
Fair value of underlying ordinary shares	$	9.53		$	6.35

Summary of Share-based Compensation Expense

Share-based compensation expense recorded as research and development and general and administrative expenses is as follows (in thousands):

	Years Ended December 31,
	2021		2020		2019
Research and development	$	3,362	$	1,331	$	332
General and administrative		2,955		1,661		387
	$	6,317	$	2,992	$	719