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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
OPERATING EXPENSES:      
Research and development $ 57,263 $ 42,224 $ 22,629
General and administrative 21,120 21,971 11,098
Total operating expenses 78,383 64,195 33,727
Loss from operations (78,383) (64,195) (33,727)
OTHER INCOME (EXPENSE), NET:      
Other income (expense) 7,318 3,133 531
Total other income (expense), net 7,318 3,133 531
Loss before provision for income taxes (71,065) (61,062) (33,196)
Provision for income taxes (111) (37) (3)
Net loss (71,176) (61,099) (33,199)
Other comprehensive income:      
Foreign exchange translation adjustment (28,331) (5,686) 4,213
Comprehensive loss $ (99,507) $ (66,785) $ (28,986)
Net loss per share attributable to ordinary shareholders-basic $ (1.82) $ (2.13) $ (31.14)
Net loss per share attributable to ordinary shareholders-diluted $ (1.82) $ (2.13) $ (31.14)
Weighted average ordinary shares outstanding-basic 39,139,693 28,654,760 1,066,208
Weighted average ordinary shares outstanding-diluted 39,139,693 28,654,760 1,066,208