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Condensed Consolidated Statement of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows from operating activities:    
Net loss $ (90,957,000) $ (165,911,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 15,366,000 12,869,000
Stock-based compensation 20,431,000 40,782,000
Loss on investments 3,693,000 2,544,000
Change in fair value of notes receivable 5,285,000 0
Change in fair value of warrant liabilities 0 (940,000)
Change in fair value of contingent consideration (1,302,000) (926,000)
Non-cash lease expense 7,379,000 5,637,000
Non-cash in-process research and development 0 16,816,000
Other non-cash activity 149,000 (442,000)
Changes in operating assets and liabilities:    
Changes in operating assets and liabilities: (4,693,000) (6,770,000)
Prepaid expenses and other current assets 462,000 1,154,000
Operating lease right-of-use assets 3,675,000 0
Other non-current assets (167,000) (707,000)
Accounts payable, accrued expenses and other current liabilities 6,419,000 10,871,000
Accounts payable, accrued expenses and other current liabilities (12,471,000) (2,912,000)
Operating lease liabilities, current and non-current (4,790,000) (4,097,000)
Other non-current liabilities 0 2,773,000
Net cash used in operating activities (51,521,000) (89,259,000)
Cash flows from investing activities:    
Purchases of marketable debt securities (191,182,000) 0
Purchases of property and equipment (7,622,000) (6,710,000)
Business acquisition 0 (5,400,000)
Other 120,000 0
Net cash used in investing activities (198,684,000) (12,110,000)
Cash flows from financing activities:    
Proceeds from exercise of stock options 0 70,000
Principal payments on finance leases (207,000) (294,000)
Contingent consideration payment 0 (621,000)
Net cash used in financing activities (207,000) (845,000)
Effect of foreign exchange rates on cash and cash equivalents 74,000 (157,000)
Net decrease in cash, cash equivalents and restricted cash (250,338,000) (102,371,000)
Cash and cash equivalents, beginning of period 561,572,000 944,073,000
Restricted cash, beginning of period 44,171,000 45,511,000
Cash, cash equivalents and restricted cash, beginning of period 605,743,000 989,584,000
Cash and cash equivalents, end of period 312,420,000 840,440,000
Restricted cash, end of period 42,985,000 46,773,000
Cash, cash equivalents and restricted cash, end of period $ 355,405,000 $ 887,213,000