Significant Collaboration Transactions - Synlogic Inc. Narrative (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Issuance of common stock pursuant to public offering, net of issuance costs			$ 98,910
Equity method investments		$ 0	1,543
Revenue remaining performance obligation amount		110,000	123,500
Deferred other income			222,600	$ 189,200
Revenue recognized		251,455	477,706	$ 313,837
Synlogic Inc
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Deferred other income		$ 100	$ 100
Common Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Issuance of common stock pursuant to public offering, net of issuance costs (in shares)			41,384,000
Issuance of common stock pursuant to public offering, net of issuance costs			$ 4
Synlogic Inc
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Equity method investments, fair value	$ 35,800
Revenue remaining performance obligation amount	30,000
Equity method investment difference between aggregated cost and underlying equity	29,800
Equity method investment	$ 80,000
Synlogic Inc | Maximum
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Deferred other income					$ 200
Synlogic Inc | Warrant Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Number of ordinary share called by each warrant (in shares)	2,500,000
Exercise price of warrants or rights (in dollars per share)	$ 9.00
Synlogic Inc | Foundry Services Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Exercise price of warrants or rights (in dollars per share)	$ 8.99
Payments for repurchase of warrants	$ 22,900
Warrant exercisable interest rate	19.99%
Cash and cash equivalents	$ 30,000
Synlogic Inc | Common Stock
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Issuance of common stock pursuant to public offering, net of issuance costs (in shares)	6,300,000
Shares issued, price per share (in dollars per share)	$ 9.00
Issuance of common stock pursuant to public offering, net of issuance costs	$ 57,100
Equity method investment ownership percentage	19.90%
Synlogic Inc | Warrants
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Equity method investments	$ 14,400