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Stock-Based Compensation - Summary of Stock-Based Compensation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total $ 229,884 $ 1,930,641 $ 1,682,565
Research and development      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total 145,879 731,996 926,730
General and administrative      
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]      
Total $ 84,005 $ 1,198,645 $ 755,835