Investments and Equity Method Investments - Schedule of Investments and Equity Method Investments (Details) - USD ($)		3 Months Ended			9 Months Ended
		Sep. 30, 2023	Sep. 30, 2022		Sep. 30, 2023	Sep. 30, 2022		Dec. 31, 2022
Net Investment Income [Line Items]
Total		$ 84,970,000			$ 84,970,000			$ 112,188,000
Equity method investments	[1]	1,120,000			1,120,000			1,543,000
(Loss) gain on investments:		(36,324,000)	$ (1,758,000)	[2]	(44,815,000)	$ (39,981,000)	[2]
Loss on equity method investments:		0	(22,711,000)	[2]	(1,516,000)	(53,764,000)	[2]
Genomatica, Inc. preferred stock
Net Investment Income [Line Items]
Equity securities		11,885,000			11,885,000			44,885,000
Synlogic, Inc. common stock
Net Investment Income [Line Items]
Equity securities		1,188,000			1,188,000			4,819,000
(Loss) gain on investments:		(1,538,000)	(1,268,000)		(3,631,000)	(9,321,000)
Synlogic, Inc. warrants
Net Investment Income [Line Items]
Equity securities		477,000			477,000			1,937,000
(Loss) gain on investments:		(618,000)	(510,000)		(1,459,000)	(3,746,000)
Marketable equity securities
Net Investment Income [Line Items]
Equity securities		18,960,000			18,960,000			20,895,000
(Loss) gain on investments:		460,000	215,000		(3,286,000)	(16,604,000)
Non-marketable equity securities
Net Investment Income [Line Items]
Equity securities		27,631,000			27,631,000			17,544,000
(Loss) gain on investments:		(1,628,000)	(195,000)		(1,628,000)	(195,000)
SAFEs
Net Investment Income [Line Items]
SAFEs		24,829,000			24,829,000			22,108,000
(Loss) gain on investments:		0	0		(1,811,000)	0
BiomEdit, LLC
Net Investment Income [Line Items]
Equity method investments	[1]	0			0			369,000
Loss on equity method investments:		0	(1,308,000)		(1,462,000)	(5,860,000)
Other
Net Investment Income [Line Items]
Equity method investments	[1]	1,120,000			1,120,000			1,174,000
Loss on equity method investments:		0	(188,000)		(54,000)	(378,000)
Genomatica, Inc.
Net Investment Income [Line Items]
(Loss) gain on investments:		(33,000,000)	0		(33,000,000)	(10,115,000)
Joyn Bio, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	(5,226,000)		0	(15,637,000)
Verb Biotics, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	0		0	(15,900,000)
Ayana, LLC
Net Investment Income [Line Items]
Loss on equity method investments:		0	$ (15,989,000)		0	$ (15,989,000)
Platform Ventures
Net Investment Income [Line Items]
Equity method investments		$ 0			$ 0			$ 0

[1] Equity method investments in Platform Ventures with a carrying value of zero as of September 30, 2023 and December 31, 2022 were excluded from the table.

[2] As adjusted to reflect the impact of the adoption of Accounting Standards Codification Topic 842, Leases (“ASC 842”) as of January 1, 2022. See Note 1 for a summary of the adjustments.