Income Taxes - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Income Tax Disclosure [Line Items]
Valuation allowance, Deferred tax asset, Increase, Amount	$ 249,979,000	$ 439,280,000
Percenetage of stockholders determining cumulative change in ownership	5.00%
Percentage points used in determining cumulative change in ownership	50.00%
Uncertain tax positions	$ 0	0
Unrecognized tax benefits, Income tax penalties and interest accrued	0	$ 0
Domestic Tax Authority [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	$ 1,838,000,000.0
Operating loss expiration year	2029
Domestic Tax Authority [Member] | Research Tax Credit Carryforward [Member]
Income Tax Disclosure [Line Items]
Operating loss expiration year	2029
Tax credit carryforward, Amount	$ 30,300,000
Domestic Tax Authority [Member] | Begin To Expire In 2029 [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	139,200,000
Domestic Tax Authority [Member] | Carried Forward Indefinitely [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	1,698,800,000
State and Local Jurisdiction [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	$ 734,100,000
Operating loss expiration year	2030
State and Local Jurisdiction [Member] | Research Tax Credit Carryforward [Member]
Income Tax Disclosure [Line Items]
Operating loss expiration year	2030
Tax credit carryforward, Amount	$ 55,700,000
State and Local Jurisdiction [Member] | Carried Forward Indefinitely [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	72,200,000
State and Local Jurisdiction [Member] | Begin To Expire In 2030 [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	661,900,000
Foreign Tax Authority [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	$ 1,400,000
Operating loss expiration year	2030
Foreign Tax Authority [Member] | Carried Forward Indefinitely [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	$ 900,000
Foreign Tax Authority [Member] | Begin To Expire In 2030 [Member]
Income Tax Disclosure [Line Items]
Operating loss carryforwards	$ 500,000