X0306 4 2021-12-06 0 0001830214 Ginkgo Bioworks Holdings, Inc. DNA 0001882756 Canton Barry C/O GINKGO BIOWORKS HOLDINGS, INC. 27 DRYDOCK AVENUE BOSTON MA 02210 0 0 1 0 Class A Common Stock 2021-12-06 4 C 0 200000 A 200000 I By Bartholomew Canton Living Trust Class A Common Stock 2021-12-07 5 G 0 E 200000 0.00 D 0 I By Bartholomew Canton Living Trust Class B Common Stock 2021-12-06 4 C 0 200000 D Class A Common Stock 200000 70189783 I By Bartholomew Canton Living Trust Class B Common Stock Class A Common Stock 3093797 3093797 D Class B Common Stock Class A Common Stock 3093797 3093797 I By Spouse Class B Common Stock Class A Common Stock 70389783 70389783 I By Reshma Padmini Shetty Living Trust Class B Common Stock Class A Common Stock 8245491 8245491 I By Reshma Padmini Shetty GRAT Class B Common Stock Class A Common Stock 8245491 8245491 I By Bartholomew Canton GRAT Class B Common Stock Class A Common Stock 1291794 1291794 I By The Asha S. Canton Irrevocable Trust Class B Common Stock Class A Common Stock 1291794 1291794 I By The Adhira S. Canton Irrevocable Trust The transactions being reported herein relate to a charitable donation of shares of Class A Common Stock. The donated shares remain subject to transfer restrictions in accordance with the Issuer's certificate of incorporation. Shares of the Class B Common Stock may be converted into shares of Class A Common Stock, on a one-to-one basis, at the option of the holder at any time and have no expiration date. Pursuant to the business combination of Soaring Eagle Acquisition Corp. and Ginkgo Bioworks, Inc. ("Legacy Ginkgo"), as contemplated by an agreement and plan of merger, dated May 11, 2021 and amended on May 14, 2021 (the "Merger Agreement"), (a) each share of Class A common stock of Legacy Ginkgo outstanding immediately prior to the effective time of the business combination was converted into approximately 49.080452 shares of the Issuer's Class A Common Stock; and (b) each share of Class B common stock of Legacy Ginkgo outstanding immediately prior to the effective time of the business combination was converted into approximately 49.080452 shares of the Issuer's Class B Common Stock. Pursuant to the Merger Agreement, each share of Class A common stock of Legacy Ginkgo, each share of Class B common stock of Legacy Ginkgo, each option of Legacy Ginkgo under Legacy Ginkgo's stock incentive plans, each award of restricted common stock of Legacy Ginkgo under Legacy Ginkgo's stock incentive plans, and each award of restricted stock units of Legacy Ginkgo under Legacy Ginkgo's stock incentive plans, in each case outstanding immediately prior to the effective time of the business combination, received a proportional amount of the approximately 188.7 million earn-out shares. /s/ Karen Tepichin, Attorney-in-fact 2021-12-08