CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK, COMMON STOCK AND STOCKHOLDERS' EQUITY (DEFICIT) - USD ($) $ in Thousands	Total	Convertible Preferred Stock (Series A-F)	Convertible Preferred Stock Series AA	Convertible Preferred Stock Series BB	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2019	$ (68,662)					$ 23,650	$ (92,312)
Temporary equity, Beginning balance, shares at Dec. 31, 2019		15,257,663
Temporary equity, Beginning balance at Dec. 31, 2019		$ 47,545
Beginning balance, shares at Dec. 31, 2019					369,491
Stock-based compensation expense	1,492					1,492
Conversion of preferred stock into common stock	47,545					47,545
Temporary equity, Conversion of preferred stock into common stock, shares		(15,257,663)
Temporary equity, Conversion of preferred stock into common stock		$ (47,545)
Conversion of preferred stock into common stock, shares					627,871
Conversion of common stock into series AA preferred stock	(17,274)					(17,274)
Temporary equity, Conversion of common stock into series AA preferred stock, shares			210,310,025
Temporary equity, Conversion of common stock into series AA preferred stock			$ 17,274
Conversion of common stock into series AA preferred stock, shares					(148,732)
Preferred stock issued in exchange for note redemption			$ 18,050
Preferred stock issued in exchange for note redemption, shares			219,764,872
Issuance of preferred stock			$ 26,087	$ 10,925
Issuance of preferred stock, shares			317,608,275	52,680,306
Issuance of common stock, net of issuance costs, shares					705,750
Exercise of options into common stock	$ 15					15
Exercise of options into common stock, Shares	16,666				16,666
Issuance of common stock related to Alvaxa IPR&D acquisition	$ 541					541
Issuance of common stock related to Alvaxa IPR&D acquisition, Shares					304,376
Net loss	(20,100)						(20,100)
Ending balance at Dec. 31, 2020	(56,443)					55,969	(112,412)
Temporary equity, Ending balance, shares at Dec. 31, 2020			747,683,172	52,680,306
Temporary equity, Ending balance at Dec. 31, 2020			$ 61,411	$ 10,925
Ending balance, shares at Dec. 31, 2020					1,875,422
Stock-based compensation expense	5,657					5,657
Conversion of preferred stock into common stock	95,828				$ 2	95,826
Temporary equity, Conversion of preferred stock into common stock, shares			(747,683,172)	(165,956,208)
Temporary equity, Conversion of preferred stock into common stock			$ (61,411)	$ (34,416)
Conversion of preferred stock into common stock, shares					19,034,069
Issuance of preferred stock				$ 23,491
Issuance of preferred stock, shares				113,275,902
Issuance of common stock, net of issuance costs	138,489				$ 1	138,488
Issuance of common stock, net of issuance costs, shares					8,030,295
Exercise of options into common stock	$ 28					28
Exercise of options into common stock, Shares	8,834				8,834
Issuance of common stock under the employee stock purchase plan	$ 80					80
Issuance of common stock under the employee stock purchase plan, Shares					11,700
Exercise of common stock warrants	1					1
Exercise of common stock warrants, Shares					1,648,709
Unrealized loss on marketable securities	(333)							$ (333)
Net loss	(36,794)						(36,794)
Ending balance at Dec. 31, 2021	$ 146,513				$ 3	$ 296,049	$ (149,206)	$ (333)
Ending balance, shares at Dec. 31, 2021					30,609,029