<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002016808</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001828811</issuerCik>
      <issuerName>Li-Cycle Holdings Corp.</issuerName>
      <secFileNumber>001-40733</secFileNumber>
      <issuerAddress>
        <com:street1>C/O LI-CYCLE CORP.</com:street1>
        <com:street2>207 Queens Quay West, Suite 590</com:street2>
        <com:city>Toronto</com:city>
        <com:stateOrCountry>A6</com:stateOrCountry>
        <com:zipCode>M5J 1A7</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>877 542-9253</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Spollen Conor</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Shares</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Wealth management Canada Inc.</name>
        <address>
          <com:street1>140 4th Avenue SW, Suite 2740</com:street1>
          <com:city>Calgary</com:city>
          <com:stateOrCountry>A0</com:stateOrCountry>
          <com:zipCode>T2P 3N3</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>500</noOfUnitsSold>
      <aggregateMarketValue>520.00</aggregateMarketValue>
      <noOfUnitsOutstanding>38380390</noOfUnitsOutstanding>
      <approxSaleDate>01/27/2025</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common shares</securitiesClassTitle>
      <acquiredDate>01/27/2025</acquiredDate>
      <natureOfAcquisitionTransaction>Common shares to be issued on settlement of previously granted RSUs</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>920</amountOfSecuritiesAcquired>
      <paymentDate>01/27/2025</paymentDate>
      <natureOfPayment>Equity Compensation</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <securitiesSoldInPast3Months>
      <sellerDetails>
        <name>Conor Spollen</name>
        <address>
          <com:street1>c/o Li-Cycle Holdings Corp.</com:street1>
          <com:street2>207 Queens Quay West, Suite 590</com:street2>
          <com:city>Toronto</com:city>
          <com:stateOrCountry>A6</com:stateOrCountry>
          <com:zipCode>M5J 1A7</com:zipCode>
        </address>
      </sellerDetails>
      <securitiesClassTitle>Common Shares</securitiesClassTitle>
      <saleDate>12/03/2024</saleDate>
      <amountOfSecuritiesSold>4970</amountOfSecuritiesSold>
      <grossProceeds>9379.38</grossProceeds>
    </securitiesSoldInPast3Months>
    <remarks>The Reporting Person will be selling an estimated amount of common shares set forth herein pursuant to automatic sell to cover transactions that do not represent a discretionary trade by the Reporting Person in order to pay the tax liability arising from the vesting and settlement of restricted stock units.  The aggregate market value estimate is based on the closing price of the Issuer's common shares on January 23, 2025 at $1.04 per common share. </remarks>
    <noticeSignature>
      <noticeDate>01/24/2025</noticeDate>
      <signature>/s/Carl DeLuca, as attorney-in-fact for Conor Spollen</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
