<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001990663</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001828811</issuerCik>
      <issuerName>Li-Cycle Holdings Corp.</issuerName>
      <secFileNumber>001-40733</secFileNumber>
      <issuerAddress>
        <com:street1>C/O LI-CYCLE CORP.</com:street1>
        <com:street2>207 Queens Quay West, Suite 590</com:street2>
        <com:city>Toronto</com:city>
        <com:stateOrCountry>A6</com:stateOrCountry>
        <com:zipCode>M5J 1A7</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>877-542-9253</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>DeLuca Carl</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Shares</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Wealth Management Canada Inc.</name>
        <address>
          <com:street1>140 4th Avenue SW; Suite 2740</com:street1>
          <com:city>Calgary</com:city>
          <com:stateOrCountry>A0</com:stateOrCountry>
          <com:zipCode>T2P-3N3</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>11060</noOfUnitsSold>
      <aggregateMarketValue>59586.86</aggregateMarketValue>
      <noOfUnitsOutstanding>178107516</noOfUnitsOutstanding>
      <approxSaleDate>08/15/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common Shares</securitiesClassTitle>
      <acquiredDate>08/10/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Common shares issued on settlement of previously granted RSUs</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>20875</amountOfSecuritiesAcquired>
      <paymentDate>08/10/2023</paymentDate>
      <natureOfPayment>Equity Compensation</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>The Reporting Person is selling the common shares set forth herein pursuant to an automatic sell to cover transaction that did not represent a discretionary trade by the Reporting Person in order to pay the tax liability arising from the vesting and settlement of restricted stock units.  Past sales per above table also include: 11,827 common shares pursuant to an automatic sell to cover transaction that did not represent a discretionary trade by the Reporting Person in order to pay the tax liability arising from the vesting and settlement of restricted stock units for an aggregate gross proceeds of $72,210.93 on September 16, 2022.</remarks>
    <noticeSignature>
      <noticeDate>08/23/2023</noticeDate>
      <signature>/s/Carl DeLuca</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
