<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>144</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001990629</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <issuerInfo>
      <issuerCik>0001828811</issuerCik>
      <issuerName>Li-Cycle Holdings Corp.</issuerName>
      <secFileNumber>001-40733</secFileNumber>
      <issuerAddress>
        <com:street1>C/O LI-CYCLE HOLDINGS CORP.</com:street1>
        <com:street2>207 Queens Quay West, Suite 590</com:street2>
        <com:city>Toronto</com:city>
        <com:stateOrCountry>A6</com:stateOrCountry>
        <com:zipCode>M5J 1A7</com:zipCode>
      </issuerAddress>
      <issuerContactPhone>877-542-9253</issuerContactPhone>
      <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Biederman Christopher J.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
      <relationshipsToIssuer>
        <relationshipToIssuer>Officer</relationshipToIssuer>
      </relationshipsToIssuer>
    </issuerInfo>
    <securitiesInformation>
      <securitiesClassTitle>Common Shares</securitiesClassTitle>
      <brokerOrMarketmakerDetails>
        <name>Morgan Stanley Wealth Management Canada Inc.</name>
        <address>
          <com:street1>140 4th Avenue SW; Suite 2749</com:street1>
          <com:city>Calgary</com:city>
          <com:stateOrCountry>A0</com:stateOrCountry>
          <com:zipCode>T2P-3N3</com:zipCode>
        </address>
      </brokerOrMarketmakerDetails>
      <noOfUnitsSold>7271</noOfUnitsSold>
      <aggregateMarketValue>39173.24</aggregateMarketValue>
      <noOfUnitsOutstanding>178107516</noOfUnitsOutstanding>
      <approxSaleDate>08/15/2023</approxSaleDate>
      <securitiesExchangeName>NYSE</securitiesExchangeName>
    </securitiesInformation>
    <securitiesToBeSold>
      <securitiesClassTitle>Common shares</securitiesClassTitle>
      <acquiredDate>08/10/2023</acquiredDate>
      <natureOfAcquisitionTransaction>Common shares issued on settlement of previously granted RSUs</natureOfAcquisitionTransaction>
      <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
      <isGiftTransaction>N</isGiftTransaction>
      <amountOfSecuritiesAcquired>13723</amountOfSecuritiesAcquired>
      <paymentDate>08/10/2023</paymentDate>
      <natureOfPayment>Equity Compensation</natureOfPayment>
    </securitiesToBeSold>
    <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
    <remarks>Reporting Person is selling the common shares set forth herein pursuant to an automatic sell to cover transaction that did not represent a discretionary trade by the Reporting Person in order to pay the tax liability arising from the vesting and settlement of restricted stock units. Past sales per above table also include 7,775 common shares pursuant to an automatic sell to cover transaction that did not represent a discretionary trade by the Reporting Person in order to pay the tax liability arising from the vesting and settlement of restricted stock units for an aggregate gross proceeds of $47,471.04 on September 16, 2022.</remarks>
    <noticeSignature>
      <noticeDate>08/23/2023</noticeDate>
      <signature>/s/Christopher Biederman</signature>
    </noticeSignature>
  </formData>
</edgarSubmission>
