X0306 4 2021-07-22 0 0001828673 HCW Biologics Inc. HCWB 0001866272 Greene Rick S. C/O HCW BIOLOGICS INC 2929 N. COMMERCE PARKWAY MIRAMAR FL 33025 1 0 0 0 Common Stock 2021-08-25 4 P 0 3611 4.1045 A 3611 D Stock Option 4.77 2021-07-22 4 A 0 20964 0.00 A 2031-07-21 Common Stock 20964 20964 D The range of prices for the shares of Common Stock is from $4.09 to $4.11. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. The option will fully vest on July 22, 2022. /s/ Hing C. Wong, as Attorney-in-Fact for Rick S. Greene 2021-08-27