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Share-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2024
Share-Based Payment Arrangement [Abstract]  
Schedule of weighted-average assumptions of fair value stock option issued to employees
The fair value of each stock option issued to employees was estimated at the date of grant using Black-Scholes with the following weighted-average assumptions:
Year Ended,
20242023
Expected volatility108.73 %97.1 %
Expected term (years)66
Risk-free interest rate4.0 %3.7 %
Expected dividend yield— %— %
Schedule of stock option activity
A summary of stock option activity is presented below:
Number of
Stock Options		Weighted-
average
Exercise
Price Per
Option		Weighted-
average
Remaining
Contractual
Term (Years)		Aggregate
Intrinsic Value
(in thousands)
Outstanding, January 1, 20246,207,664$6.91 7.95$6,044 
Granted2,170,3523.17 
Exercised(171,981)0.00034 
Forfeited/expired(920,760)8.54 
Outstanding, December 31, 20247,285,275$5.76 7.61$942 
Exercisable, December 31, 20243,629,105$7.93 7.13$790 
Schedule of share based compensation expense
Share based compensation expense is classified in the consolidated statements of operations and comprehensive loss as follows (in thousands):
Year ended
December 31,
2024		Year ended
December 31,
2023
Research and development$1,680 $2,011 
General and administrative3,029 3,044 
Total$4,709 $5,055