X0306 4 2021-02-23 0 0001439725 BIODESIX INC BDSX 0001828131 O'Kane Kieran 2970 WILDERNESS PLACE SUITE 100 BOULDER CO 80301 0 1 0 0 Chief Commercial Officer Stock Options (Right to buy) 0.77 2021-02-23 4 A 0 4212 0 A 2030-04-14 Common Stock 4212 4212 D Stock Options (Right to buy) 0.77 2022-03-10 4 A 0 4211 0 A 2030-04-14 Common Stock 4211 8423 D Stock Options (Right to buy) 2.29 2022-03-10 4 A 0 6162 0 A 2022-03-10 2032-03-09 Common Stock 6162 6162 D On April 15, 2020, the Reporting Person was granted an option to purchase 8,423 shares (as-adjusted for the 0.1684664-for-1 reverse stock split effected on October 19, 2020), the vesting of which was subject to the Issuer's satisfaction of certain performance criteria for each of the 2020 and 2021 fiscal years. On February 23, 2021, the Compensation Committee of the Issuer's board of directors (the "Compensation Committee") confirmed the performance criteria were met for fiscal year 2020, resulting in the vesting of 4,212 shares underlying the option. On March 10, 2022, the Compensation Committee confirmed the performance criteria were met for fiscal year 2021, resulting in the vesting of 4,211 shares underlying the option. /s/ Robin Harper Cowie as Attorney-in-Fact for Kieran O'Kane 2022-03-14