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Share-Based Compensation - Stock options activity (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Share-Based Compensation          
Number of shares available for grant     363,095 1,861,856  
Stock options          
Beginning balance (in shares) 15,712,434 3,209,063 3,209,063    
Exercised (194,977)        
Ending balance (in shares) 14,960,960   15,712,434 3,209,063  
Vested and exercisable as of December 31, 2021 4,549,923   463,816 1,375  
Weighted Average Exercise Price          
Beginning balance (in dollars per share) $ 2.19        
Ending balance (in dollars per share) 2.27   $ 2.19    
Exercised 0.54        
Weighted Average Exercise Price $ 0.80        
Weighted Average Remaining Contractual Life (in years)          
Outstanding 8 years 8 months 12 days   9 years 2 months 12 days    
Vested and exercisable as of ending of year 8 years   8 years 3 months 18 days    
Aggregate intrinsic value          
Outstanding     $ 120,491,000 $ 16,094,000 $ 2,817,000
Vested and exercisable as of ending of year     $ 36,579,000    
Weighted-average grant date fair value of stock options granted     $ 4,034 $ 3,701  
Share- based compensation expense     $ 0    
Future share-based compensation for unvested stock options     $ 19,628,000    
Weighted-average Period     2 years 9 months    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value $ 5,901,000 $ 17,510,000 $ 14,161,000 $ 1,030,000  
2018 Equity Incentive Plan          
Share-Based Compensation          
Number of shares authorized     8,209,568 6,672,721  
Number of shares available for grant     363,095 1,861,856  
Share-based Payment Arrangement, Option          
Share-Based Compensation          
Vesting period (in years) 4 years   4 years    
Vesting expiration period 10 years   10 years    
Aggregate intrinsic value          
Weighted-average grant date fair value of stock options granted     $ 9.05 $ 2.54  
Share- based compensation expense $ 7,757,000 $ 991,000 $ 6,433,000 $ 3,558,000  
Share-based Payment Arrangement, Option | 2018 Equity Incentive Plan          
Stock options          
Beginning balance (in shares) 5,031,310 3,209,063 3,209,063 1,081,579  
Number of options granted     3,457,020 3,251,443  
Exercised     (1,247,236) (307,778)  
Cancelled/Forfeited/Expired     (387,537) (816,181)  
Ending balance (in shares)     5,031,310 3,209,063 1,081,579
Vested and exercisable as of December 31, 2021     1,284,624    
Weighted Average Exercise Price          
Beginning balance (in dollars per share) $ 6.85 $ 1.57 $ 1.57 $ 2.31  
Ending balance (in dollars per share)     6.85 1.57 $ 2.31
Granted     9.37 2.60  
Exercised     1.68 1.56  
Cancelled/Forfeited/Expired     2.00 $ 2.03  
Weighted Average Exercise Price     $ 2.33    
Weighted Average Remaining Contractual Life (in years)          
Outstanding       9 years 1 month 6 days 8 years 10 months 24 days
Restricted Stock [Member]          
Share-Based Compensation          
Vesting period (in years)     4 years    
Aggregate intrinsic value          
Weighted-average grant date fair value of stock options granted     $ 1.78 $ 1.69  
Share- based compensation expense $ 148,000 $ 148,000 $ 890,000 $ 915,000  
Weighted-average Period     4 months 28 days