SCHEDULE 13G/A 0001831942 XXXXXXXX LIVE 2 Common Shares, without par value 12/31/2025 0001827401 BRIGHT MINDS BIOSCIENCES INC. 10919W405 400 N ABERDEEN ST SUITE 900 CHICAGO IL 60642 Rule 13d-1(c) Commodore Capital LP DE 0.00 18851.00 0.00 18851.00 18851.00 0.3 IA PN Commodore Capital Master LP E9 0.00 18851.00 0.00 18851.00 18851.00 0.3 PN BRIGHT MINDS BIOSCIENCES INC. 400 N ABERDEEN ST, SUITE 900, CHICAGO, ILLINOIS, 60642. Commodore Capital LP Commodore Capital Master LP Each a "Filer." The address for Commodore Capital LP is 444 Madison Avenue, Floor 35, New York, NY 10022.The address for Commodore Capital Master LP is c/o Maples Corporate Services Limited, Ugland House, South Church Street, PO Box 309, Grand Cayman KY1-1104, Cayman Islands. See Item 4 of the cover page for each Filer. Y See Item 9 of the cover page for each Filer. This report on Schedule 13G is being filed by Commodore Capital LP (the "Firm") and Commodore Capital Master LP ("Commodore Master"). The Firm is the investment manager to Commodore Master. As of December 31, 2025 the Firm may be deemed to beneficially own an aggregate of 18,851 shares of Common Shares (the "Common Shares") of Bright Minds Biosciences Inc. (the "Issuer"). The Firm, as the investment manager to Commodore Master, may be deemed to beneficially own these securities. Michael Kramarz and Robert Egen Atkinson are the managing partners of the Firm and exercise investment discretion with respect to these securities. Ownership percentages are based on 7,635,789 Common Shares reported as issued and outstanding as of September 30, 2025, based on information reported in the Issuer's Annual Report on Form 40-F, filed with the Securities and Exchange Commission on December 23, 2025. See item 11 of the cover page for each Filer. See item 5 of the cover page for each Filer. See item 6 of the cover page for each Filer. See item 7 of the cover page for each Filer. See item 8 of the cover page for each Filer. Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Commodore Capital LP Michael Kramarz 02/17/2026 Commodore Capital Master LP Michael Kramarz 02/17/2026