X0306 4 2023-01-25 0 0001680367 Shattuck Labs, Inc. STTK 0001827232 Pandite Arundathy N. C/O SHATTUCK LABS, INC. 500 W. 5TH STREET, SUITE 1200 AUSTIN TX 78701 0 1 0 0 Chief Medical Officer Common Stock 2023-01-25 4 A 0 37875 0.00 A 175792 D Stock Option (Right to Buy) 3.57 2023-01-25 4 A 0 69750 0.00 A 2033-01-25 Common Stock 69750 69750 D Consists of 37,875 restricted stock units, which will vest in four equal annual installments beginning on January 25, 2024, subject to the Reporting Person's continued service to the Issuer. This option represents a right to purchase a total of 69,750 shares of the Issuer's common stock, one quarter of which will vest on January 25, 2024, with the remaining three quarters vesting in equal monthly installments through January 25, 2027, subject to the Reporting Person's continued service to the Issuer. /s/ Erin Ator Thomson, Attorney-in-fact for Arundathy N. Pandite 2023-01-27