X0306 4 2022-01-10 0 0001680367 Shattuck Labs, Inc. STTK 0001827232 Pandite Arundathy N. C/O SHATTUCK LABS, INC. 500 W. 5TH STREET, SUITE 1200 AUSTIN TX 78701 0 1 0 0 Chief Medical Officer Common Stock 2022-01-10 4 A 0 34738 0.00 A 140904 D Stock Option (Right to Buy) 7.43 2022-01-10 4 A 0 69475 0.00 A 2032-01-10 Common Stock 69475 69475 D Consists of 34,738 restricted stock units, which will vest in four equal annual installments beginning on January 10, 2023, subject to the Reporting Person's continued service to the Issuer. This option represented a right to purchase a total of 69,475 shares of the Issuer's common stock, one quarter of which will vest on January 10, 2023, with the remaining three quarters vesting in equal monthly installments through January 10, 2026, subject to the Reporting Person's continued service to the Issuer. /s/ Erin Ator Thomson, Attorney-in-fact for Arundathy N. Pandite 2022-01-12