144 0001827198 XXXXXXXX LIVE 0001581280 Twist Bioscience Corp 001-38720 681 GATEWAY BLVD. SOUTH SAN FRANCISCO CA 94080 800-719-0671 Laponis Adam Officer Common Fidelity Brokerage Services LLC

900 Salem Street Smithfield RI 02917

4000 240000.00 61311704 04/17/2026 NASDAQ Common 08/20/2025 Restricted Stock Vesting Issuer N 161 08/20/2025 Compensation Common 08/20/2025 ESPP Purchase Issuer N 266 08/20/2025 Cash Common 10/01/2025 Restricted Stock Vesting Issuer N 2511 10/01/2025 Compensation Common 02/20/2026 Restricted Stock Vesting Issuer N 1062 02/20/2026 Compensation N Adam Laponis

681 Gateway Blvd South San Francisco CA 94080

Common 02/12/2026 7000 350000.00 Adam Laponis

681 Gateway Blvd South San Francisco CA 94080

Common 02/23/2026 2085 97389.93 Adam Laponis

681 Gateway Blvd South San Francisco CA 94080

Common 04/09/2026 2597 129561.48 Adam Laponis

681 Gateway Blvd South San Francisco CA 94080

Common 04/14/2026 3000 165000.00 04/17/2026 05/08/2025 /s/ Gary Redman, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Adam Laponis