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Segment Information
6 Months Ended
Jun. 30, 2025
Segment Reporting [Abstract]  
Segment Information

11. Segment Information

Operating segments are identified as components of an enterprise about which separate discrete financial information is available for evaluation by the chief operating decision-maker in making decisions regarding resource allocation and assessing performance. The Company is a clinical-stage biopharmaceutical company and has not generated any product revenue from its CAB antibody-based products. The Company’s operations are organized and reported as a single reportable segment, which includes all activities related to the discovery, development, and commercialization of its CAB products. The Company’s CODM, its chief executive officer, reviews operating results on an aggregate basis and manages the operations as a single operating segment. The measure of segment assets is reported on the balance sheets as total assets. The CODM evaluates performance and allocates resources based on net income or loss that also is reported on the condensed statements of operations and comprehensive loss as net loss, and cash used in operations.

The following table provides R&D expenses by program with a reconciliation to net loss for the periods indicated, which are regularly reviewed by the CODM:

 

Three Months Ended
June 30,

 

 

Six Months Ended
June 30,

 

 

2025

 

 

2024

 

 

2025

 

 

2024

 

 

(in thousands)

 

 

 

 

Program expenses:

 

 

 

 

 

 

 

 

 

 

 

Mecbotamab vedotin, BA3011 (CAB AXL-ADC)

$

3,051

 

 

$

3,500

 

 

$

5,992

 

 

$

8,833

 

Ozuriftamab vedotin, BA3021 (CAB ROR2-ADC)

 

1,208

 

 

 

2,023

 

 

 

3,285

 

 

 

4,564

 

Evalstotug, BA3071 (CAB CTLA-4)

 

3,045

 

 

 

2,447

 

 

 

3,224

 

 

 

5,055

 

BA3182 (CAB EpCAM x CAB CD3)

 

2,136

 

 

 

1,206

 

 

 

3,076

 

 

 

2,377

 

Other CAB Programs

 

728

 

 

 

1,629

 

 

 

1,799

 

 

 

3,258

 

Total program expenses

 

10,168

 

 

 

10,805

 

 

 

17,376

 

 

 

24,087

 

Personnel and related

 

2,145

 

 

 

3,347

 

 

 

5,603

 

 

 

6,770

 

Equity-based compensation

 

567

 

 

 

1,164

 

 

 

1,342

 

 

 

2,244

 

Facilities and other

 

804

 

 

 

882

 

 

 

1,718

 

 

 

1,949

 

Total research and development expenses

 

13,684

 

 

 

16,198

 

 

 

26,039

 

 

 

35,050

 

General and administrative expenses

 

 

 

 

 

 

 

 

 

 

 

Personnel and related

 

1,577

 

 

 

1,938

 

 

 

3,680

 

 

 

3,906

 

Equity-based compensation

 

810

 

 

 

1,332

 

 

 

1,680

 

 

 

2,553

 

Facilities and other

 

2,576

 

 

 

2,504

 

 

 

4,862

 

 

 

4,920

 

Total general and administrative expenses

 

4,963

 

 

 

5,774

 

 

 

10,222

 

 

 

11,379

 

Interest and other income (loss)

 

(64

)

 

 

900

 

 

 

2,216

 

 

 

2,123

 

Net loss and comprehensive loss

$

(18,711

)

 

$

(21,072

)

 

$

(34,045

)

 

$

(44,306

)