Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023
Cash flows from operating activities
Net loss	$ (69,776)	$ (123,462)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	925	1,221
Loss on disposal of property and equipment	0	2
Change in fair value of warrant liability	(807)	0
Stock-based compensation	8,921	13,544
Changes in operating assets and liabilities:
Prepaid expenses and other assets	2,903	(11)
Accounts payable and accrued expenses	(13,461)	5,284
Right-of-use assets and lease liabilities, net	(641)	(593)
Net cash used in operating activities	(71,936)	(104,015)
Cash flows from investing activities
Purchases of property and equipment	0	(98)
Net cash used in investing activities	0	(98)
Cash flows from financing activities
Proceeds from issuance of common stock and warrants, net of issuance costs	9,215	0
Proceeds from issuance of common stock under Employee Stock Purchase Plan	342	336
Payments for taxes related to net settlement of equity awards	(46)	(259)
Net cash provided by financing activities	9,511	77
Net decrease in cash and cash equivalents	(62,425)	(104,036)
Cash and cash equivalents, beginning of period	111,471	215,507
Cash and cash equivalents, end of period	49,046	111,471
Supplemental disclosure of non-cash investing and financing activities
Equity issuance costs included in accounts payable and accrued expense	445	0
Tax related to net settlement of equity award included in accounts payable and accrued expenses	$ 0	$ 6