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Convertible and other debt - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Dec. 31, 2018
Apr. 30, 2018
Dec. 31, 2015
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Apr. 30, 2020
Aug. 31, 2018
Debt Instrument [Line Items]                
interest expense       $ 3 $ 1,389 $ 1,630    
Conversion price description   The 2018 Notes were amended in April 2020 to add a discount to the conversion prices such that they were convertible (i) automatically into preferred stock upon a qualified equity financing, with a conversion price of 80% of the lowest purchase price per share of preferred stock paid by investors in such qualified equity financing, (ii) automatically convert into common stock upon an initial public offering, with a conversion price of 80% of the price per share of common stock paid by investors in such initial public offering, and (iii) upon the election of each note holder, into Class C preferred units, with a conversion price per share of $2.7153136.       The 2019 Notes were convertible (i) automatically into preferred stock upon a qualified equity financing, with a conversion price of 80% of the lowest purchase price per share of preferred stock paid by investors in such qualified equity financing, (ii) automatically into common stock upon an initial public offering, with a conversion price of 80% of the price per share of common stock paid by investors in such initial public offering, and (iii) upon the election of each note holder, into Class C preferred units, with a conversion price per share of $2.7153136.    
Gain (loss) on extinguishment of long-term debt       690 (2,883) $ 0    
Other Debt                
Debt Instrument [Line Items]                
Debt Instrument Outstanding Principal Amount         $ 700      
Debt Instrument, Decrease, Forgiveness       700        
Amendment and settlement of convertible notes (class D units)                
Debt Instrument [Line Items]                
Conversion price         $ 0.51554931 $ 0.412439448    
Promissory notes payable to aggregate principal amount         $ 21,800      
accrued interest         4,700      
Convertible notes carrying value         $ 27,900      
Amendment and settlement of convertible notes (class D units) | Himalaya Parent L L C                
Debt Instrument [Line Items]                
Gain (loss) on extinguishment of long-term debt       2,700        
Issuance of Series D convertible preferred stock in connection with settlement of convertible promissory notes, shares         59,164,808      
Convertible note issued       30,600        
Pfizer Notes                
Debt Instrument [Line Items]                
Fee paid to lenders     $ 500          
interest expense         $ 600 $ 1,000    
Pfizer Notes | Pfizer Inc                
Debt Instrument [Line Items]                
Accrued interest rate     8.00%          
Conversion price     $ 3.394142          
Pfizer Notes | Pfizer Inc | Unsecured Convertible Promissory Note                
Debt Instrument [Line Items]                
Note issued     $ 10,000          
2018 Notes                
Debt Instrument [Line Items]                
Note issued $ 5,000              
Accrued interest rate               8.00%
Conversion price             $ 2.7153136 $ 3.394142
Fee paid to lenders           200    
interest expense         $ 400 $ 400    
Gain (loss) on extinguishment of long-term debt       $ (200)        
amortization of debt discounts $ 2,200              
2019 Notes                
Debt Instrument [Line Items]                
Accrued interest rate           8.00%    
Conversion price         $ 0.86866 $ 2.7153136    
interest expense         $ 300 $ 100    
derivative liability           1,800    
Promissory notes payable to aggregate principal amount           4,000    
Due to related parties           1,500    
Additional paid-in capital and debt discount           $ 500    
outstanding principal balance             $ 2,500  
2020 Notes                
Debt Instrument [Line Items]                
Accrued interest rate         8.00%      
interest expense         $ 100      
derivative liability         1,200      
Promissory notes payable to aggregate principal amount         2,800      
Due to related parties         $ 500      
maturity dates         December 7, 2020      
outstanding principal balance         $ 100      
outstanding principal plus accrued interest divided         $ 0.86866