Balance sheet details - Schedule of Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Balance Sheet Related Disclosures [Abstract]
Accounts payable	$ 1,179	$ 2,456
Accrued compensation	2,671	2,804
Accrued research and development	13,501	4,852
Accrued equity issuance costs	0	1,143
Other accrued expenses	1,073	813
Total	$ 18,424	$ 12,068