<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-08-08</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001826470</issuerCik>
        <issuerName>Petco Health &amp; Wellness Company, Inc.</issuerName>
        <issuerTradingSymbol>WOOF</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001942465</rptOwnerCik>
            <rptOwnerName>Heffelfinger Jason</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O PETCO HEALTH AND WELLNESS COMPANY,</rptOwnerStreet1>
            <rptOwnerStreet2>INC., 10850 VIA FRONTERA</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92127</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Services Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Class A Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>31728</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Employee Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>18.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2031-01-13</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Class A Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>30000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Includes 28,790 restricted stock units (&quot;RSUs&quot;) granted under the Petco Health and Wellness Company, Inc. 2021 Equity Incentive Plan (the &quot;2021 Plan&quot;). Each RSU represents the right to receive one share of Class A common stock of the Issuer (&quot;Class A Common Stock&quot;). 13,476 outstanding RSUs will vest in equal installments on each of 1/13/2023, 7/13/2023, and 1/13/2024. The remaining 15,314 outstanding RSUs will vest in the following installments: (i) 34% on the first anniversary of 3/18/2022 (the &quot;RSU Grant Date&quot;); (ii) 16.5% on the date that is 18 months following the RSU Grant Date; (iii) 16.5% on the second anniversary of the RSU Grant Date; (iv) 16.5% on the date that is 30 months following the RSU Grant Date; and (v) 16.5% on the third anniversary of the RSU Grant Date.</footnote>
        <footnote id="F2">Represents options to purchase Class A Common Stock granted under the 2021 Plan. The options vested and will vest in the following installments: (i) 34% on the first anniversary of 1/13/2021 (the &quot;Option Grant Date&quot;); (ii) 16.5% on the date that is 18 months following the Option Grant Date; (iii) 16.5% on the second anniversary of the Option Grant Date; (iv) 16.5% on the date that is 30 months following the Option Grant Date; and (v) 16.5% on the third anniversary of the Option Grant Date.</footnote>
    </footnotes>

    <remarks>Exhibit 24.1 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Ilene Eskenazi, as Attorney-in-Fact</signatureName>
        <signatureDate>2022-08-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
