X0306 4 2020-09-28 0 0001299130 PACIFIC BIOSCIENCES OF CALIFORNIA, INC. PACB 0001825421 Kim Susan G. PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 1305 O'BRIEN DRIVE MENLO PARK CA 94025 0 1 0 0 Chief Financial Officer Common Stock 2020-09-28 4 A 0 150000 0.00 A 150000 D Stock Option (right to buy) 9.60 2020-09-28 4 A 0 400000 0.00 A 2021-09-28 2030-09-28 Common Stock 400000 400000 D Each share is represented by a Restricted Stock Unit ("RSU"). The RSUs will vest in equal annual installments on September 28 of each of 2021, 2022, 2023, and 2024, provided that the Reporting Person continues to serve through each vesting date. 1/4 of the shares subject to the option will vest on the one year anniversary of the date of grant, and the balance of shares will vest monthly thereafter over the next three years, provided that the Reporting Person continues to serve through each vesting date. /s/ Eric Schaefer, Attorney-in-fact 2020-09-30