Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities:
Net loss	$ (333,659)	$ (617,179)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	75,710	90,880
Depreciation and amortization	8,335	6,768
Noncash operating lease expense	3,931	0
Accretion of discount on short-term investments, net	(383)	0
Change in fair value of warrants liability	0	326,900
Gain on loan extinguishment	0	(4,183)
Other adjustments	122	0
Changes in operating assets and liabilities:
Accounts receivable	(1,545)	(560)
Prepaid expenses and other current assets	(3,738)	(12,114)
Other assets	2,279	(659)
Accounts payable	3,136	(313)
Amounts due to joint development partners	(2,603)	5,642
Accrued expenses and other current liabilities	(3,632)	16,488
Operating lease liabilities	(3,927)	0
Other liabilities	(17)	1,965
Net cash used in operating activities	(255,991)	(186,365)
Cash flows from investing activities:
Purchases of property and equipment	(9,809)	(12,218)
Purchases of short-term investments	(200,162)	0
Purchases of intangible assets	(196)	(302)
Proceeds from disposal of property and equipment	27	100
Net cash used in investing activities	(210,140)	(12,420)
Cash flows from financing activities:
Proceeds from issuance of redeemable convertible preferred stock, net of offering costs	0	54,693
Proceeds from the issuance of common stock under the Employee Stock Purchase Plan	2,286	0
Proceeds from exercise of warrants for redeemable convertible preferred stock	0	183,007
Proceeds from exercised stock options	1,710	782
Proceeds from issuance of common stock upon initial public offering, net of offering costs	0	1,030,965
Proceeds from issuance of common stock related to private placement	0	35,000
Return of guarantee deposit on related party loan	0	3,715
Principal payments on related party loan	0	(4,398)
Payment of third-party costs in connection with initial public offering	0	(2,812)
Principal payments on capital lease obligations	0	(586)
Principal payments on finance lease obligations	(929)	0
Principal payments on loans	(1,126)	(353)
Net cash provided by financing activities	1,941	1,300,013
Effect of exchange rate changes on cash, cash equivalents, and restricted cash	(1,931)	55
Net increase (decrease) in cash, cash equivalents, and restricted cash	(466,121)	1,101,283
Cash, cash equivalents, and restricted cash - beginning of period	1,339,092	312,351
Cash, cash equivalents, and restricted cash - end of period	872,971	1,413,634
Reconciliation of cash, cash equivalents, and restricted cash to the condensed consolidated balance sheets:
Cash and cash equivalents	871,360	1,412,128
Restricted cash included in prepaid expenses and other current assets	1,611	1,506
Total cash, cash equivalents, and restricted cash	872,971	1,413,634
Supplemental disclosure of cash flow information:
Cash paid for interest	681	575
Supplemental schedule of non-cash investing and financing activities:
Acquisitions of property and equipment included in liabilities	3,783	1,987
Accretion of redeemable convertible preferred stock	0	4,135
Vesting of early exercised stock options	63	63
Exercise of liability-classified warrants	0	369,352
Conversion of redeemable convertible preferred stock to common stock upon initial public offering	0	1,282,916
Issuance costs incurred in connection with initial public offering included in current liabilities	$ 0	$ 779