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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Net loss $ (111,903) $ (385,160)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 27,527 6,289
Depreciation and amortization 2,735 2,110
Change in fair value of warrants liability 0 326,900
Other adjustments (8) 0
Changes in operating assets and liabilities:    
Accounts receivable (202) (285)
Prepaid expenses and other current assets (422) (3,360)
Operating lease right-of-use assets 1,222 0
Other assets (758) (152)
Accounts payable 227 9,237
Amounts due to/from related parties 0 4,558
Amounts due to joint development partners 454 0
Accrued expenses and other current liabilities (18,286) (8,217)
Operating lease liabilities (1,642) 0
Other liabilities 426 1,347
Net cash used in operating activities (100,630) (46,733)
Cash flows from investing activities:    
Purchases of property and equipment (1,356) (1,210)
Purchases of intangible assets (40) (87)
Proceeds from disposal of property and equipment 19 100
Net cash used in investing activities (1,377) (1,197)
Cash flows from financing activities:    
Proceeds from issuance of redeemable convertible preferred stock, net of offering costs 0 61,631
Proceeds from the issuance of common stock under the Employee Stock Purchase Plan 1,292 0
Proceeds from exercise of warrants for redeemable convertible preferred stock 0 183,007
Proceeds from early exercised stock options 871 253
Principal payments on related party loan 0 (613)
Principal payments on capital lease obligations 0 (191)
Principal payments on finance lease obligations (293) 0
Principal payments on loans (358) (117)
Net cash provided by financing activities 1,512 243,970
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 155 1,100
Net change in cash, cash equivalents, and restricted cash (100,340) 197,140
Cash, cash equivalents, and restricted cash - beginning of period 1,339,092 312,351
Cash, cash equivalents, and restricted cash - end of period 1,238,752 509,491
Reconciliation of cash, cash equivalents, and restricted cash to the condensed consolidated balance sheets:    
Cash and cash equivalents 1,237,246 508,706
Restricted cash included in prepaid expenses and other current assets 1,506 785
Total cash and cash equivalents, and restricted cash 1,238,752 509,491
Supplemental disclosure of cash flow information:    
Cash paid for interest 281 195
Supplemental schedule of non-cash investing and financing activities:    
Acquisitions of property and equipment included in current liabilities 1,038 1,939
Accretion of redeemable convertible preferred stock 0 4,135
Vesting of early exercised stock options 21 21
Exercise of liability-classified warrants $ 0 $ 369,352