Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Schedule of Loss before Provision for Income Taxes

Loss before provision for income taxes consisted of the following (in thousands):

	Years Ended December 31,
	2019		2020		2021
US	$	(57,789)	$	(95,000)	$	(673,941)
Cayman Islands	(1,144)		(50,358)		—
Foreign	(25,950)		(32,512)		(58,732)
Loss before provision for income taxes	$	(84,883)	$	(177,870)	$	(732,673)

Schedule of Provision for Income Taxes

Provision for income taxes consisted of the following (in thousands):

	Years Ended December 31,
	2019		2020		2021
Current:
US	$	—	$	—	$	—
Cayman Islands	—		—		—
Foreign	—		—		—
Total current provision	—		—		—
Deferred:
US	$	—	$	—	$	—
Cayman Islands	—		—		—
Foreign	—		—		—
Total deferred provision	—		—		—
Total provision for income taxes	$	—	$	—	$	—

Schedule of Effective Income Tax Rate Reconciliation

	Years Ended December 31,
	2019		2020		2021
Tax at statutory rate	$	—	$	—	$	(153,862)
State and local taxes (net of federal tax benefit)	—		—		(3,531)
Tax rate change	—		—		11,317
Change in valuation allowances	26,011		38,984		99,129
Foreign tax rate differential	(20,883)		(30,633)		2,354
Research and development tax credits	(5,841)		(8,874)		(15,465)
Warrant fair market value adjustment	—		—		68,649
Section 162(m) limitation - officers compensation	—		—		6,672
Uncertain tax position reserves	724		364		1,800
Stock-based compensation	—		(354)		(16,344)
Other	(11)		513		(719)
Total	$	—	$	—	$	—

Schedule of Unrecognized Tax Position

A reconciliation of the beginning and ending balance to total unrecognized tax position is as follows (in thousands):

	Years Ended December 31,
	2019		2020		2021
Unrecognized tax benefit, beginning of year	$	2,850	$	4,029	$	4,766
Increases related to current year tax positions	1,179		737		2,134
Unrecognized tax benefit, end of year	$	4,029	$	4,766	$	6,900

Schedule of Deferred Tax Assets and Liabilities

Significant components of the Company’s deferred tax assets and liabilities are as follows (in thousands):

	Years Ended December 31,
	2019		2020		2021
Deferred tax assets:
Net operating loss carryforwards	$	39,489	$	74,417	$	155,088
Tax credit carryforwards	4,879		9,833		18,769
Lease liability	1,320		1,116		797
Other	225		631		2,479
Stock-based compensation	—		264		8,887
Gross deferred tax assets	45,913		86,261		186,020
Valuation allowance	(43,985)		(84,852)		(184,892)
Net deferred tax assets	1,928		1,409		1,128
Deferred tax liabilities:
Property, plant and equipment	438		352		395
Intangible assets	10		—		—
Capital lease assets	1,480		1,057		733
Net deferred tax liabilities	1,928		1,409		1,128
Net deferred tax asset/(liability)	$	—	$	—	$	—