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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of Estimated Grant-Date Fair Value of ESPP The estimated grant-date fair value of the ESPP purchase rights was calculated using the Black-Scholes option-pricing model, based on the following assumptions:
Year Ended December 31, 2021
Risk-free interest rate
0.06%
Expected dividend yield
Expected volatility
97.10%
Expected term (in years)
0.50
Fair value of common stock
$44.39
Summary of Share Option Activities A summary of the stock option activities, including the CEO Performance Award, for the year ended December 31, 2021 is as follows (in thousands, except share amounts, per share amounts, and years):
 Options
Outstanding
Weighted-
Average
Exercise
Price
Weighted-
Average
Remaining
Life
(Years)
Aggregate
Intrinsic
Value
Outstanding at December 31, 202013,295,497$1.29 7.99$97,986 
Granted
3,767,96822.36 
Exercised
(8,580,984)0.14 
Cancelled/Forfeited
(797,703)1.27 
Outstanding at December 31, 20217,684,778$12.91 9.04$188,722 
Vested and exercisable at December 31, 20211,996,923$4.38 8.80$62,843 
Summary of Estimated Grant Date Fair Value of Company's Stock Based Option Awards The estimated grant-date fair value of the Company’s stock-based option awards was calculated using the Black-Scholes option-pricing model, based on the following assumptions:
 Years Ended December 31,
 201920202021
Risk-free interest rate
0.14% - 0.44%
0.33% - 1.25%
Expected dividend yield
Expected volatility
51.00% – 60.00%
50.00%
Expected term (in years)
2.21 – 6.06
4.05 - 6.22
Fair value of common stock
$1.52 – $8.24
$32.18 - $47.79
Summary of Nonvested Restricted Stock Unit Awards The following table summarizes the activity related to RSUs for the year ended December 31, 2021:
 RSUs
Outstanding
Weighted-
Average Grant
Date Fair Value
per Share
Unvested and Outstanding at December 31, 20201,100,000$14.14 
Granted
6,197,22947.57 
Vested(1,217,573)22.42 
Cancelled
(129,858)47.42 
Unvested and outstanding at December 31, 20215,949,798$46.54 
Vested and outstanding at December 31, 202115,603$40.35 
Summary of Nonvested Shareholder Value Awards Activity The following table summarizes the activity related to SVAs for the year ended December 31, 2021:
 SVAs
Outstanding
 Weighted-
Average Grant
Date Fair Value
per Share
Unvested and Outstanding at December 31, 20203,653,146$3.20 
Vested
(3,070,459)3.08 
Cancelled
(267,128)5.77 
Unvested and outstanding at December 31, 2021315,559$5.29 
Vested and outstanding at December 31, 2021$— 
Summary of Total Stock-based Compensation Expense
 Years Ended December 31,
 201920202021
Research and development$— $917 $71,201 
Selling, general and administrative— 11,846 51,395 
Total stock-based compensation expense
$— $12,763 $122,596