X0306 4 2021-09-15 0 0001823593 TuSimple Holdings Inc. TSP 0001607429 Francis Karen C 9191 TOWNE CENTRE DRIVE, STE 600 SAN DIEGO CA 92122 1 0 0 0 Class A Common Stock 2021-09-15 4 M 0 4420 A 80402 D Class A Common Stock 20000 I By trust Class A Common Stock 20000 I By trust Restricted Stock Unit 2021-09-15 4 M 0 4420 D Class A Common Stock 4420 4420 D The Reporting Person received Restricted Stock Units ("RSUs") that represent a contingent right to receive one share of Class A Common Stock for each RSU upon the satisfaction of applicable vesting conditions. The shares were issued pursuant to vested RSUs. The shares are held by the Karen C. Francis Second Restated Revocable Trust dated 1.30.2012, of which the Reporting Person is trustee. The shares are held by the Richard C. DeGolia Trust dated 8.27.2004, of which the Reporting Person's spouse is trustee. The Reporting Person was granted RSUs which represent a contingent right to receive one share of Class A Common Stock for each RSU. The RSUs are subject to a service-based vesting requirement, which shall be satisfied over a one-year period. 25% of the RSUs vested on March 15, 2021 and 25% of the RSUs shall vest each quarter thereafter, subject to the Reporting Person's continuous service with the issuer. /s/ Laura Donald - Attorney-in-Fact 2021-09-17