X0306 4 2021-04-19 0 0001823593 TuSimple Holdings Inc. TSP 0001607429 Francis Karen C 9191 TOWNE CENTRE DRIVE, STE 600 SAN DIEGO CA 92122 1 0 0 0 Common Stock 2021-04-19 4 C 0 20000 A 20000 I By trust Common Stock 2021-04-19 4 C 0 20000 A 20000 I By trust Common Stock 2021-04-19 4 J 0 20000 D 0 I By trust Common Stock 2021-04-19 4 J 0 20000 D 0 I By trust Common Stock 2021-04-19 4 J 0 60000 D 0 D Class A Common Stock 2021-04-19 4 J 0 20000 A 20000 I By trust Class A Common Stock 2021-04-19 4 J 0 20000 A 20000 I By trust Class A Common Stock 2021-04-19 4 J 0 60000 A 60000 D Class A Common Stock 2021-04-19 4 P 0 7142 40.00 A 67142 D Series E Convertible Preferred Stock 2021-04-19 4 C 0 20000 D Class A Common Stock 20000 0 I By trust Series E Convertible Preferred Stock 2021-04-19 4 C 0 20000 D Class A Common Stock 20000 0 I By trust The total represents shares received upon conversion of shares of Series E Convertible Preferred Stock. The reported security converted into the Issuer's Common Stock on a one-for-one basis automatically immediately prior to the closing of the issuer's initial public offering without payment of further consideration. The shares have no expiration date. The shares are held by the Karen C. Francis Second Restated Revocable Trust dated 1.30.2012, of which the Reporting Person is trustee. The shares are held by the Richard C. DeGolia Trust dated 8.27.2004, of which the Reporting Person's spouse is trustee. Pursuant to a reclassification exempt under Rule 16b-7, each share of Common Stock was automatically reclassified into one share of Class A Common Stock immediately prior to the completion of the Issuer's initial public offering of Class A Common Stock. The shares are subject to the issuer's right of repurchase, which shall lapse over a three-year period in equal quarterly installments after December 15, 2020, subject to the Reporting Person's continuous service with the issuer. Represents shares purchased in the Issuer's initial public offering. /s/ James Mullen - Attorney-in-Fact 2021-04-21