X0306 4 2020-09-15 0 0001640266 Voyager Therapeutics, Inc. VYGR 0001823262 Vitale Nancy C/O VOYAGER THERAPEUTICS, INC., 75 SIDNEY STREET CAMBRIDGE MA 02139 1 0 0 0 Stock Option (Right to Buy) 10.85 2020-09-15 4 A 0 30000 0 A 2030-09-15 Common Stock 30000 30000 D The stock option was issued pursuant to the 2015 Stock Option and Incentive Plan of Voyager Therapeutics, Inc. in accordance with its director compensation policy. The vesting commencement date of the option is the grant date. The shares of common stock underlying the option are scheduled to vest in equal quarterly installments through September 15, 2024, subject to the Reporting Person's continued service. /s/ Allison Dorval, as Attorney-in-Fact for Nancy Vitale 2020-09-16