<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
<headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001835544</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>3</amendmentNo>
      <securitiesClassTitle>Common Stock</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>05/11/2026</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001822791</issuerCik>
        <issuerName>Clene Inc.</issuerName>
        <issuerCusips>
          <issuerCusipNumber>G8959N130</issuerCusipNumber>
        </issuerCusips>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>6550 SOUTH MILLROCK DRIVE, SUITE G50</com:street1>
          <com:city>SALT LAKE CITY</com:city>
          <com:stateOrCountry>UT</com:stateOrCountry>
          <com:zipCode>84121</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Ugwumba Chidozie</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>1351071.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>1351071.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>1351071.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.7</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>With regard to the number of shares reported in response to (5), (7), and (9) above, the number represents (i) 176,713 shares of Common Stock of the Issuer, (ii) 375,000 shares of Common Stock issuable upon exercise of Tranche A Warrants that are immediately exercisable, (iii) 375,000 shares of Common Stock issuable upon exercise of Tranche B Warrants that are immediately exercisable, and (iv) 424,358 shares of Common Stock issuable upon exercise of the Common Stock Purchase Warrant that is immediately exercisable. The foregoing is based on 12,778,307 shares of the Issuer's Common Stock issued and outstanding, as represented in the Issuer's Form 10-Q filed with the Securities and Exchange Commission on May 14, 2026.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Clene Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>6550 SOUTH MILLROCK DRIVE, SUITE G50, SALT LAKE CITY, UTAH, 84121.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Chidozie Ugwumba </filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>c/o SymBiosis Capital Management, LLC 609 SW 8th St., Suite 510, Bentonville, AR 72712</principalBusinessOfficeOrResidenceAddress>
        <citizenship>United States of America</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>1,351,071</amountBeneficiallyOwned>
        <classPercent>9.7%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>1,351,071</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>1,351,071</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Ugwumba Chidozie</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Chidozie Ugwumba</signature>
        <title>Reporting Person</title>
        <date>05/15/2026</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>
