X0206 3/A 2020-12-30 2021-01-04 0 0001822791 Clene Inc. CLNN 0001251956 MATLIN DAVID J 61 CEDAR POINT LANE SAG HARBOR NY 11963 true false false false Warrants (Right to buy) 0.01 2021-06-28 2021-12-30 Common Stock 12500.00 D Warrants (Right to buy) 0.01 2021-06-28 2021-12-30 Common Stock 50000.00 I By Trust This Form 3 amendment is being filed to report 12,500 warrants owned by Mr. Matlin and 50,000 warrants owned by the Matlin Family Trust 2020 acquired in a private placement on December 30, 2020, which warrants were inadvertently omitted from the original From 3 filed on January 4, 2021. The warrants are owned by the Matlin Family Trust 2020. Mr. Matlin in the trustee of the Matlin Family Trust 2020. The warrants owned by the Matlin Family Trust 2020 may be deemed to be beneficially owned by Mr. Matlin. /s/ Jerry Miraglia POA 2021-07-21