X0508 4 2025-11-13 0001822791 Clene Inc. CLNN 0001876030 McLaughlin Vallerie 6550 SOUTH MILLROCK DRIVE SUITE G50 SALT LAKE CITY UT 84121 1 0 stock option 7.30 2025-11-13 4 A 0 2083 0 A 2035-11-12 common stock 2083 2083 D This option was granted on November 13, 2025 as an option for 2,083 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $7.30 per share. The options vest immediately upon grant. /s/ Jerome T. Miraglia POA 2025-11-14