Notes Payable (Details) - USD ($)	1 Months Ended				3 Months Ended		6 Months Ended
	May 31, 2022	May 31, 2021	Apr. 30, 2019	Feb. 28, 2019	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021	Sep. 30, 2021	May 31, 2020
Notes Payable (Details) [Line Items]
Debt issuance costs							$ 30,000	$ 471,000
Minimum cash balance for loan covenant		$ 5,000,000.0
2019 MD Loan [Member]
Notes Payable (Details) [Line Items]
Term loan				$ 500,000
Interest rate				8.00%
Phantom shares, description				The 2019 MD Loan established “Phantom Shares” at issuance based on 119,907 shares of Common Stock.
Interest income (expense)						$ 200,000		(300,000)
Interest expense					$ 10,000		20,000
2019 Cecil Loan [Member]
Notes Payable (Details) [Line Items]
Term loan			$ 100,000
Interest rate			8.00%
Phantom shares, description			The 2019 Cecil Loan established “Phantom Shares” at issuance based on 23,981 shares of Common Stock.
Interest income (expense)						36,000		(54,000)
Interest expense					$ 2,000		$ 4,000
PPP Note [Member]
Notes Payable (Details) [Line Items]
Note payable											$ 600,000
2021 Avenue Loan [Member] | Notes Payable [Member]
Notes Payable (Details) [Line Items]
Term loan		30,000,000.0
Interest rate					11.35%		11.35%		9.85%
Interest expense					$ 700,000	200,000	$ 1,500,000	200,000
Accrued debt issuance costs		600,000
Amortization of Debt Issuance Costs		$ 46,951
Conditions for future funding, description		Funding of Tranche 2 is subject to (a) our receipt of $5.0 million financing through the state of Maryland; (b) our achievement of a statistically significant result in certain clinical trials (“Performance Milestone 1”); (c) our receipt of net proceeds of at least $30.0 million from the sale and issuance of our equity securities between May 2, 2021 and December 31, 2022; and (d) mutual agreement of us and Avenue.
Rate of interest, description							The 2021 Avenue Loan bears interest at a variable rate equal to the sum of (i) the greater of (a) the prime rate or (b) 3.25%, plus (ii) 6.60%. As of June 30, 2022 and December 31, 2021, the interest rate was 11.35% and 9.85%, respectively.
Additional payment upon maturity, description							On the maturity date, an additional payment equal to 4.25% of the funded loans, currently equal to $0.9 million (the “Final Payment”), is due in addition to the remaining unpaid principal and accrued interest.
Additional final payment at debt maturity		$ 900,000
Minimum funding from maryland state incentive program		5,000,000.0
Equity offering proceeds required for tranche 2 funding		$ 30,000,000.0
Warrant to purchase shares (in Shares)		115,851
Common stock at an exercise price (in Dollars per share)		$ 8.63
Tranche warrant adjustment description		Upon the funding of Tranche 2, the Avenue Warrant shall be adjusted to include an additional estimated 245,832 shares of Common Stock, which is equal to 5% of the principal amount of Tranche 2, divided by the five (5)-day VWAP per share as of the end of trading on the last trading day before the issuance of Tranche 2.
Convertible note payable					5,000,000.0		$ 5,000,000.0		$ 5,000,000.0
Minimum cash balance for loan covenant		$ 5,000,000.0
Equity offering proceeds required to remove financial covenants		30,000,000.0
Conversion feature							$ 5,000,000.0
Conversion percentage of common stock price for convertible note payable							120.00%
Convertible note issuable shares							482,703
Unamortized debt discount and issuance costs					300,000		$ 300,000		$ 400,000
Amortization of debt discount					100,000	23,000	100,000	23,000
Interest expense					200,000	100,000	400,000	100,000
Coupon interest expense					$ 100,000	$ 100,000	$ 300,000	$ 100,000
Debt Instrument, Interest Rate, Effective Percentage					16.95%	17.93%	16.95%	17.93%
Fair value of warrant		1,500,000
Financing costs		500,000
2021 Avenue Loan [Member] | Tranche one [Member]
Notes Payable (Details) [Line Items]
First loan amount		20,000,000.0
Funded amount		15,000,000.0
Additional funded amount										$ 5,000,000.0
2021 Avenue Loan [Member] | Tranche Two [Member]
Notes Payable (Details) [Line Items]
Unfunded amount		10,000,000.0
2022 MD Loan Member
Notes Payable (Details) [Line Items]
Term loan	$ 3,000,000.0
Interest rate	6.00%
Interest expense					$ 2,000		$ 2,000
Debt issuance costs	$ 31,000
Monthly installments of principal and interest amount		33,306
Line of Credit Facility, Current Borrowing Capacity					$ 700,000		$ 700,000
2022 MD Loan Member | Maximum [Member]
Notes Payable (Details) [Line Items]
Installment interest amount		$ 15,000,000