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    <periodOfReport>2022-02-02</periodOfReport>

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    <issuer>
        <issuerCik>0001822691</issuerCik>
        <issuerName>GreenLight Biosciences Holdings, PBC</issuerName>
        <issuerTradingSymbol>ENVI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
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            <rptOwnerCik>0001543112</rptOwnerCik>
            <rptOwnerName>Morningside Venture Investments Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/OTHC MGMT SERVICES SAM 2ND FL LEPRINCE</rptOwnerStreet1>
            <rptOwnerStreet2>DE GALLES, 3-5 AVE DES CITRONNIERS</rptOwnerStreet2>
            <rptOwnerCity>MONACO</rptOwnerCity>
            <rptOwnerState>O9</rptOwnerState>
            <rptOwnerZipCode>MC 98000</rptOwnerZipCode>
            <rptOwnerStateDescription>MONACO</rptOwnerStateDescription>
        </reportingOwnerAddress>
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            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
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    <footnotes>
        <footnote id="F1">In connection with the closing of the Issuer's business combination transaction, all Class A Common Stock converted into the same number of shares of the Issuer's Common Stock without payment or further consideration. The Class A Common Stock had no expiration date.</footnote>
        <footnote id="F2">Frances Anne Elizabeth Richard, Jill Marie Franklin, Peter Stuart Allenby Edwards and Cheung Ka Ho, are the directors of Morningside Venture Investments Limited (&quot;Morningside&quot;) and share voting and dispositive power with respect to the securities held by Morningside and MVIL, LLC (&quot;MVIL LLC&quot;), Morningside's wholly-owned subsidiary.  Cheng Yee Wing and Wong See Wai are the managers of MVIL LLC and share voting and dispositive power with respect to the securities held by MVIL LLC.  Ms. Richard, Ms. Franklin, Mr. Edwards and Mr. Cheung each disclaim beneficial ownership of the securities owned by Morningside.  Ms. Cheng and Mr. Wong each disclaim ownership of the securities owned by MVIL LLC.</footnote>
        <footnote id="F3">Represent shares held by MVIL LLC.</footnote>
        <footnote id="F4">Represent shares of Class A Common Stock received in exchange for shares of GreenLight BioSciences, Inc. in connection with the business combination transaction of the Issuer.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Frances Anne Elizabeth Richard, for Morningside Venture Investments Limited</signatureName>
        <signatureDate>2022-02-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
