Condensed Consolidated Statements of Stockholders’ Equity (Deficit) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning balance at Dec. 31, 2021	$ 96,871	$ 4	$ 361,133	$ (10)	$ (264,256)
Beginning balance (in shares) at Dec. 31, 2021		41,299,720
Increase (Decrease) in Stockholders' Equity
Issuance of common stock upon exercise of stock options and employee stock purchase plan	384		384
Issuance of common stock upon exercise of stock options and employee stock purchase plan (in shares)		129,895
Stock-based compensation expense	3,244		3,244
Unrealized gains on marketable securities	(1,184)			(1,184)
Net loss	(26,914)				(26,914)
Ending balance at Mar. 31, 2022	72,401	$ 4	364,761	(1,194)	(291,170)
Ending balance (in shares) at Mar. 31, 2022		41,429,615
Beginning balance at Dec. 31, 2021	96,871	$ 4	361,133	(10)	(264,256)
Beginning balance (in shares) at Dec. 31, 2021		41,299,720
Increase (Decrease) in Stockholders' Equity
Net loss	(54,227)
Ending balance at Jun. 30, 2022	47,632	$ 4	369,300	(3,189)	(318,483)
Ending balance (in shares) at Jun. 30, 2022		41,627,912
Beginning balance at Mar. 31, 2022	72,401	$ 4	364,761	(1,194)	(291,170)
Beginning balance (in shares) at Mar. 31, 2022		41,429,615
Increase (Decrease) in Stockholders' Equity
Issuance of common stock upon exercise of stock options and employee stock purchase plan	1,030		1,030
Issuance of common stock upon exercise of stock options and employee stock purchase plan (in shares)		198,297
Stock-based compensation expense	3,509		3,509
Unrealized gains on marketable securities	(1,995)			(1,995)
Net loss	(27,313)				(27,313)
Ending balance at Jun. 30, 2022	47,632	$ 4	369,300	(3,189)	(318,483)
Ending balance (in shares) at Jun. 30, 2022		41,627,912
Beginning balance at Dec. 31, 2022	$ 112	$ 4	377,232	(3,986)	(373,138)
Beginning balance (in shares) at Dec. 31, 2022	41,803,436	41,803,436
Increase (Decrease) in Stockholders' Equity
Issuance of common stock upon exercise of stock options and employee stock purchase plan	$ 102		102
Issuance of common stock upon exercise of stock options and employee stock purchase plan (in shares)		21,322
Stock-based compensation expense	4,572		4,572
Unrealized gains on marketable securities	1,116			1,116
Net loss	(30,488)				(30,488)
Ending balance at Mar. 31, 2023	(24,586)	$ 4	381,906	(2,870)	(403,626)
Ending balance (in shares) at Mar. 31, 2023		41,824,758
Beginning balance at Dec. 31, 2022	$ 112	$ 4	377,232	(3,986)	(373,138)
Beginning balance (in shares) at Dec. 31, 2022	41,803,436	41,803,436
Increase (Decrease) in Stockholders' Equity
Net loss	$ (59,975)
Ending balance at Jun. 30, 2023	$ (49,350)	$ 4	386,478	(2,719)	(433,113)
Ending balance (in shares) at Jun. 30, 2023	41,852,438	41,852,438
Beginning balance at Mar. 31, 2023	$ (24,586)	$ 4	381,906	(2,870)	(403,626)
Beginning balance (in shares) at Mar. 31, 2023		41,824,758
Increase (Decrease) in Stockholders' Equity
Issuance of common stock upon exercise of stock options and employee stock purchase plan	102		102
Issuance of common stock upon exercise of stock options and employee stock purchase plan (in shares)		27,680
Stock-based compensation expense	4,470		4,470
Unrealized gains on marketable securities	151			151
Net loss	(29,487)				(29,487)
Ending balance at Jun. 30, 2023	$ (49,350)	$ 4	$ 386,478	$ (2,719)	$ (433,113)
Ending balance (in shares) at Jun. 30, 2023	41,852,438	41,852,438