Collaboration Agreements (Details) $ in Thousands	1 Months Ended			3 Months Ended			6 Months Ended
	Jan. 31, 2022 USD ($)	Dec. 31, 2021 USD ($) program target	Jul. 31, 2020 USD ($)	Jun. 30, 2023 USD ($)	Sep. 30, 2022 USD ($)	Jun. 30, 2022 USD ($)	Jun. 30, 2023 USD ($)	Jun. 30, 2022 USD ($)	Dec. 31, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative
Revenue				$ 5,599		$ 4,490	$ 10,908	$ 8,410
Upfront payment received			$ 15,000
Maximum | Sales based
Collaborative Arrangement and Arrangement Other than Collaborative
Amount receivable for achievement of milestones			165,000
Maximum | Research Development And Regulatory
Collaborative Arrangement and Arrangement Other than Collaborative
Amount receivable for achievement of milestones			$ 245,000
Eli Lilly
Collaborative Arrangement and Arrangement Other than Collaborative
Number of additional targets | target		3
Number of programs | program		6
Number of targets | target		5
Deferred revenue				309,800			309,800		$ 319,800
Revenue				5,200		4,200	10,000	8,000
Upfront payment received	$ 300,000						300,000
Cost Sharing Allocation		50.00%
Eli Lilly | Sales Based Milestone
Collaborative Arrangement and Arrangement Other than Collaborative
Amount receivable for achievement of milestones		$ 180,000
Optout milestone receivable upon achievement		360,000
Eli Lilly | Maximum | Research Development And Regulatory
Collaborative Arrangement and Arrangement Other than Collaborative
Amount receivable for achievement of milestones		10,000
Optout milestone receivable upon achievement		$ 70,000
Merck
Collaborative Arrangement and Arrangement Other than Collaborative
Unsatisfied portion of the performance obligation				16,100			16,100		$ 17,000
Merck | Research Development And Regulatory
Collaborative Arrangement and Arrangement Other than Collaborative
Amount receivable for achievement of milestones				240,000			240,000
Merck | Merck Collaboration Agreement
Collaborative Arrangement and Arrangement Other than Collaborative
Revenue				$ 400		$ 300	$ 1,000	$ 400
Payment received for achievement of milestones					$ 5,000